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1.
J Biophotonics ; 17(1): e202300360, 2024 01.
Article in English | MEDLINE | ID: mdl-38168892

ABSTRACT

Regenerative medicine, which utilizes stem cells for tissue and organ repair, holds immense promise in healthcare. A comprehensive understanding of stem cell characteristics is crucial to unlock their potential. This study explores the pivotal role of optical microscopy in advancing regenerative medicine as a potent tool for stem cell research. Advanced optical microscopy techniques enable an in-depth examination of stem cell behavior, morphology, and functionality. The review encompasses current optical microscopy, elucidating its capabilities and constraints in stem cell imaging, while also shedding light on emerging technologies for improved stem cell visualization. Optical microscopy, complemented by techniques like fluorescence and multiphoton imaging, enhances our comprehension of stem cell dynamics. The introduction of label-free imaging facilitates noninvasive, real-time stem cell monitoring without external dyes or markers. By pushing the boundaries of optical microscopy, researchers reveal the intricate cellular mechanisms underpinning regenerative processes, thereby advancing more effective therapeutic strategies. The current study not only outlines the future of regenerative medicine but also underscores the pivotal role of optical microscopy in both structural and functional stem cell imaging.


Subject(s)
Microscopy , Regenerative Medicine , Regenerative Medicine/methods , Microscopy/methods , Stem Cells
2.
F1000Res ; 12: 463, 2023.
Article in English | MEDLINE | ID: mdl-37405233

ABSTRACT

Background: Organ shortage is a global issue and it is imperative to take steps to bridge this gap. In the Indian context, despite its demographic dividend, the rate of organ donation has been abysmally low. This emphasizes a need to demystify the antecedents of organ donation intention among the Indian population. Methods: Using a cross-sectional research design and adopting a post-positivism research philosophy, this study identified 259 respondents by adopting a purposive sampling approach and data on knowledge of organ donation was collected using a structured, pretested questionnaire. Results: Awareness of organ donation law in India is low on specific issues and respondents from the health science & medicine discipline scored better on knowledge about organ donation. The findings show that most participants had heard about organ donation and had a favourable attitude toward it. The primary sources of information on organ donation were television and newspapers, and healthcare service providers. A complementary partial median is established (ß = .217, t = 5.889, p < .001) which implies that willingness to discuss with family significantly mediates the association between attitude towards organ & tissue donation and willingness to sign the donor card. Conclusion: This study revealed that there is a general awareness of organ and tissue donation among the Indian population, but they lack clarity on certain specific issues. Mass media has to be effectively used to build awareness campaigns revolving around enhancing knowledge on a specific issue and building acceptance of the concept of organ and tissue donation.


Subject(s)
Health Knowledge, Attitudes, Practice , Tissue and Organ Procurement , Humans , Cross-Sectional Studies , India , Surveys and Questionnaires
3.
F1000Res ; 12: 75, 2023.
Article in English | MEDLINE | ID: mdl-38476970

ABSTRACT

BACKGROUND: In the healthcare domain, patients' trust in the hospital plays an instrumental role in determining the behavioral intention of the patient. This article attempts to investigate the impact of service quality perception on behavioral intention with the mediating effect of trust in the hospital and patient satisfaction. METHODS: This research was carried out in multispecialty hospitals located in Bangalore Urban and Mysore districts of Karnataka during August 2021. This was a questionnaire-based study and the sample size was 242. Statistical Package for the Social Science (SPSS) 27.0 and SmartPLS 3.0 software was used to analyze the data. RESULTS: The findings revealed that perceived service quality significantly influences trust through patient satisfaction (observed partial mediation) and patient satisfaction significantly impacts behavioral intention through trust (observed partial mediation). CONCLUSION: This study empowers hospital managers to understand the factors influencing behavioral intention. Healthcare professionals must ensure that good quality service is delivered to enhance patient satisfaction and trust in adverse services, which influence behavioral intention among the patients.


Subject(s)
Hospitals , Trust , Humans , Cross-Sectional Studies , India , Patient Satisfaction
4.
J Forensic Leg Med ; 17(2): 84-6, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20129427

ABSTRACT

Determination of individuality is one of the prime concerns in forensic investigation. The study of fingerprints is widely used in providing a clue regarding identity. The present study was undertaken to study the sex differences in fingerprint ridge density in the Indian population. The study done on 100 males and 100 females revealed that significant sex differences occur in the fingerprint ridge density. The present study shows a statistically significant difference in fingerprint ridge densities of male and female fingerprints in people of Indian origin. A mean fingerprint ridge density of 12 ridges/25 mm(2) or less is found to be more likely to be of males and a mean ridge count of more the 12 ridges/25 mm(2) is more likely to be of female origin.


Subject(s)
Dermatoglyphics , Sex Characteristics , Adolescent , Adult , Female , Humans , India , Male , Young Adult
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