[Ensuring continuity of care at the time of COVID-19: challenges for the Dakar Integrated Support Center for Addictions]. / Assurer la continuité des soins au temps de la COVID-19 : défis pour le centre de traitement des addictions à Dakar.

The COVID-19 pandemic has an impact on health systems, whose modes of adaptation and response on the ground are still poorly documented and are evolving. The Dakar Integrated Support Center for Addictions (CEPIAD) has been implementing risk reduction since 2014, particularly with drug users. The COVID-19 pandemic and related public health measures were an obstacle to its attendance by patients, in particular due to movement restriction. In addition to the implementation of individual and collective preventive measures in the center, CEPIAD has experimented "take-home" for methadon that is generally provided daily through directly observed treatment. The center has also taken care of amnestied incarcerated cannabis users. Several aspects of this experience, perceived positively, could be relevant outside the pandemic context.

Laryngeal Papillomatosis in Adults: Assessment for Ten Years at the ENT Department of the National University Hospital of Fann (Dakar, Senegal).

OBJECTIVES: The aim of this study was to describe the epidemiological, diagnostic, and therapeutic aspects of adult laryngeal papillomatosis in Senegal. Patients and Methods. This is a retrospective descriptive study of patients aged above 18 years with laryngeal papillomatosis and followed at the ENT department of the NUH of Fann between 01 January 2009 and 31 December 2018. RESULTS: The mean age at diagnosis was 37.74 years and a sex ratio of 0.93. The 20-29 age group was the most represented (45.2%). The average consultation delay was 8.34 years. All patients had dysphonia at the moment of the diagnostic and in 35.5% of cases, and it was associated with laryngeal dyspnea. Glottis localization was present in all our patients, i.e., 100% of the cases. A tracheotomy was performed in 9.67% of cases. All of our patients have had their papilloma peeled per endoscopic with tweezers. No cases of malignant degeneration were found in our study. CONCLUSION: Laryngeal papillomatosis is the most common benign tumor of the larynx in both children and adults. Despite the progress of endoscopy and antiviral treatments, its treatment poses many problems in our undermedicalized countries.

Schwannome endonasal à localisation turbinale inférieure. A propos d'un cas

Introduction : Le schwannome est une tumeur bénigne développée aux dépens des cellules de Schwann des nerfs périphériques. La localisation endonasale en particulier au niveau des cornets est rare. Observation : Nous rapportons le cas d'une femme de 23 ans reçue dans notre structure pour une masse de la fosse nasale droite localisée au niveau du cornet inférieur, obstruant totalement la lumière nasale, sans envahissement local. Après un bilan endoscopique et radiologique, l'exérèse a été effectuée par voie endoscopique endonasale. L'analyse de la pièce opératoire avait mis en évidence un schwannome. Avec un recul de 24 mois nous n'avons pas noté de récidive. Conclusion : Le schwannome à point de départ turbinal inférieur constitue une entité rare. Il doit être considéré dans le diagnostic différentiel d'une tumeur bénigne unilatérale des cavités naso-sinusiennes

Laryngeal papillomatosis in Senegal: A ten-year experience.

OBJECTIVES: The objectives of this study were to describe the epidemiological, clinical and therapeutic characteristics of laryngeal papillomatosis in the Fann teaching hospital ENT department in Dakar, Senegal. PATIENTS AND METHODS: We retrospectively reviewed all cases of laryngeal papillomatosis managed in the Fann teaching hospital ENT department between 1st January 2006 and 31st December 2015. Epidemiological, clinical and therapeutic characteristics of laryngeal papillomatosis were studied. Statistical analysis was performed with SPSS 18 software. RESULTS: The median age at diagnosis was 11 years and the sex ratio was 1.88. The mean time to consultation was 4.5 years. The predominant symptom was dysphonia, present in all cases, followed by laryngeal dyspnoea in 64.6% of cases. The glottic area was involved in all patients. Tracheostomy was performed in 20.8% of cases. All patients in our study underwent endoscopic excision of the lesions. CONCLUSION: Laryngeal papillomatosis is the most common benign tumor in children, but it can also occur in adults. Treatment has been revolutionized by progress in endoscopy and antiviral therapy. However, tracheostomy still occupies an important place in our practice.

Manejo quirúrgico de los carcinomas diferenciados de tiroides Experiencia en un país de bajos ingresos / SURGICAL MANAGEMENT OF DIFFERENTIATED THYROID CARCINOMAS. EXPERIENCE IN A LOW INCOME COUNTRY

ience in the management of differentiated thyroid carcinomas in a low- income country. Materials and Methods: We performed a retrospective study in our department where 21 cases of differentiated thyroid carcinomas were recorded from February 2001 to December 2010. Results: We performed 334 thyroidectomies for 326 patients. Of this group, 21 differentiated thyroid carcinomas were diagnosed. Differentiated thyroid carcinomas represented 6.4% of all thyroid neoplasm managed during the same period (n=326). Median age was 44 years (range 13 - 75 years). Male to female ratio was 1:20. Six (6) patients underwent primary hemithyroidectomy in other institutions while the fifteen left were entirely managed in our clinic. Of them, one patient was referred with positive fine needle aspiration cytology for papillary thyroid carcinoma (incidental detection by fine needle aspiration biopsy) and another had history of sinus pyriform fistula. Pathology of surgical specimens showed 13 cases of papillary thyroid carcinomas and 8 cases of follicular thyroid carcinomas with association to Hashimoto thyroiditis and Grave's disease in respectively in 1 case. Twenty cases were incidentally discovered by thyroid surgery and undergone completion thyroidectomy with prophylactic central neck dissection, completion thyroidectomy alone, modified lateral neck dissection alone and surveillance respectively in 13, 1, 1 and 6 cases. Complications of thyroid surgery were bilateral recurrent laryngeal nerve paralysis and hematoma respectively in 1 case. Median hospital stay was 5 days ranged from 3 to 15 days. During the follow-up period, most of our patients were lost of follow-up. Conclusion: Management guidelines of differentiated thyroid carcinomas are well established but not applicable to low- income country for several reasons. National guidelines, based on further researches, must then be implemented to improve our practice

A Rare Cause of Upper Airway Obstruction in a Child.

Ventricular band cyst is a rare condition in children but can result in severe upper airway obstruction with laryngeal dyspnea or death. The diagnosis should be considered in any stridor in children with previous history of intubation or respiratory infections. We report a case of a 4-year-old girl, received in an array of severe respiratory distress, emergency endoscopy was done, and a large ventricular tape band cyst obstructing the air way was found. Complete excision was made, and postoperative prophylaxis tracheotomy was done. The postoperative course was uneventful with improvement of clinical and endoscopic signs.

Kyste valléculaire symptomatique de l'adulte. A propos d'un cas

Les kystes valléculaires encore appelés kystes épiglottiques ou kystes basi-linguaux sont des kystes canalaires qui traduisent l'obstruction et la rétention de mucus au niveau des canaux excréteurs, des glandes sous-muqueuses. Ils peuvent se manifester chez le nouveau-né par une détresse respiratoire aiguë, chez l'adulte ils sont le plus souvent asymptomatiques et sont découverts lors d'une laryngoscopie indirecte ou lors d'une intubation.L'objectif de ce travail était de rapporter un cas de kyste valléculaire symptomatique chez un adulte de 50 ans pris en charge au service d'ORL et de chirurgie cervico-faciale de Hôpital Général de Grand Yoff, Dakar, Sénégal. La nasofibroscopie a objectivé une formation kystique arrondie siégeant au niveau de la vallécule gauche. La tomodensitométrie cervico-faciale a mis en évidence une masse valléculaire gauche hypodense homogène plaquant l'épiglotte contre le plan glottique. Au plan thérapeutique, nous avions effectué une ponction première du kyste suivie de son exérèse complète par électrocoagulation de la base d'implantation. Les suites opératoires étaient simples

Paralysie récurrentielle bilatérale : l'aryténoïdopexie est-elle toujours compétitive ?

Introduction : La Paralysie Récurrentielle (PR) bilatérale en adduction est une situation clinique dramatique. Le traitement repose sur la chirurgie par voie endoscopique couplée au laser. Ce procédé thérapeutique est inaccessible dans beaucoup de pays en développement. La chirurgie par voie externe peut-elle constituer une alternative ? Matériel et méthodes : Nous avons mené une étude rétrospective portant sur 20 patients, porteurs d'une PR bilatérale en adduction post-thyroïdectomie, sur une période de 12 ans. Tous les malades ont été traités par abord chirurgical cervical externe. L'appréciation des résultats se faisait sur la possibilité de décanulation et la qualité de la voix.Résultats : Tous les malades étaient de sexe féminin avec un âge moyen de 43 ans. La PR était une complication de la thyroïdectomie totale dans 85% des cas et subtotale dans 15% des cas. L'abord latéral du larynx nous a permis de réaliser 16 aryténoïdopexies selon King et 2 aryténoïdectomies associées à une cordopexie selon Graaf Woodman. L'abord antérieur par thyrotomie, effectué dans 4 cas, a permis de réaliser une aryténoïdectomie dans 1 cas et une cordo-aryténoïdectomie dans 3 cas. La décanulation a été effective chez tous les malades après un délai moyen de 30 jours. Après analyse perceptuelle, chez 11 patients, la qualité de la voix était jugée bonne dans 4cas (36.63%), passable dans 2 (18.18%) et mauvaise dans 5 (45.46%).Conclusion : Nos résultats sont satisfaisants et comparables à ceux des séries des pays développés, usant des procédés endoscopiques au laser

Séroprévalence de la toxoplasmose chez les femmes enceintes au CHU Aristide Le Dantec de Dakar de 2011 à 2014

La toxoplasmose est une parasitose bénigne due à Toxoplasma gondii. Cependant, elle peut être sévère chez l'immunodéprimé ou chez le fœtus après une transmission congénitale. Toutefois ces complications peuvent être évitées par des moyens de prévention dont la clé repose sur la détermination de la sérologie toxoplasmique chez la femme enceinte. L'objectif de cette étude est de déterminer la séroprévalence de la toxoplasmose chez les femmes enceintes venues au laboratoire de parasitologie-mycologie du CHU Aristide Le Dantec de Dakar de 2011 à 2014. Un total de 341 femmes enceintes d'âge compris entre 19 et 49 ans avec une moyenne d'âge de 26 ans a été reçu au laboratoire pour un sérodiagnostic de la toxoplasmose. La technique immuno-enzymatique en phase solide (EIA) a été utilisée pour la détermination du titre en anticorps IgM et IgG. Une sérologie positive a été trouvée chez 157 femmes enceintes représentant une prévalence de 46,03%. Trois profils immunologiques ont été retrouvés : IgG+/IgM+, IgG-/IgM+ et IgG+/IgM-respectivement chez 12 femmes enceintes (3,52%), chez 18 femmes enceintes (4,98%) et chez 128 femmes enceintes (37,54%). Ceci justifie une amélioration du dépistage sérologique et de son suivi afin de prévenir les formes graves chez le fœtus et chez l'enfant

Corps étrangers laryngo-trachéo-bronchiques : à propos de 130 cas

Objectifs : Les objectifs de notre étude étaient de décrire les aspects épidémiologiques, diagnostiques et thérapeutiques des corps étrangers des voies respiratoires inférieures à la clinique d'ORL et de chirurgie cervico-faciale du centre Hospitalier National et Universitaire de Fann. Patients et méthodes : Il s'agit d'une étude rétrospective, couvrant la période du 1er janvier 2011 au 31 décembre 2013. Nous avons colligé, durant cette période, 130 dossiers de patients âgés de moins de 18 ans qui étaient reçus pour inhalation de corps étrangers. Les endoscopies blanches étaient exclues. Les paramètres étudiés étaient : l'âge, le sexe, la présence ou non d'un syndrome de pénétration, les signes fonctionnels, le délai de consultation, le traitement effectué, la localisation endoscopique, la nature du corps étranger, les données de l'imagerie, l'indication de la trachéotomie et les complications. L'analyse des données était effectuée avec le logiciel Sphinx Lexica V 4.5 2003. Résultats : L'âge moyen de nos patients était de 3,84 ans avec des extrêmes allant de 4 mois à 17 ans. Une prédominance féminine était notée avec un sex-ratio de 0,91. Les patients évacués d'autres pays représen- taient 6,9% des cas. Le délai moyen de consultation était de 8,05 jours. Le syndrome de pénétration était retrouvé dans 78,5% des cas. La radiographie standard mettait en évidence un corps étranger radio-opaque dans 33,1% des cas. La localisation laryngée était la plus fréquente, elle représentait 26,7% des cas. La graine d'arachide était le corps étranger le plus fréquemment retrouvé soit 39,2%. Onze patients étaient trachéotomisés. Quatre cas de décès ont été rapportés soit 3% des cas.Conclusion : L'inhalation d'un corps étranger est un problème de santé publique. L'augmentation de l'incidence de cet accident et la transition épidémiologique impose une meilleure prévention

[Keratomycosis due to Fusarium oxysporum treated with the combination povidone iodine eye drops and oral fluconazole]. / Kératomycose à Fusarium oxysporum traitée par l'association de la povidone iodée en collyre et du fluconazole per os.

In developing countries where systemic antifungal are often unavailable, treatment of filamentous fungi infection as Fusarium is sometimes very difficult to treat. We report the case of a keratomycosis due to Fusarium oxysporum treated by povidone iodine eye drops and oral fluconazole. The diagnosis of abscess in the cornea was retained after ophthalmological examination for a 28-year-old man with no previous ophthalmological disease, addressed to the Ophthalmological clinic at the University Hospital Le Dantec in Dakar for a left painful red eye with decreased visual acuity lasting for 15 days. The patient did not receive any foreign body into the eye. Samples by corneal scraping were made for microbiological analysis and the patient was hospitalized and treated with a reinforced eye drops based treatment (ceftriaxone+gentamicin). The mycological diagnosis revealed the presence of a mold: F. oxysporum, which motivated the replacement of the initial treatment by eye drops containing iodized povidone solution at 1% because of the amphotericin B unavailability. Due to the threat of visual loss, oral fluconazole was added to the local treatment with eye drops povidone iodine. The outcome was favorable with a healing abscess and visual acuity amounted to 1/200th. Furthermore, we noted sequels such as pannus and pillowcase. The vulgarization of efficient topical antifungal in developing countries would be necessary to optimize fungal infection treatment.

[Pseudo-tumoral aspergillus rhinosinusitis: About two cases]. / Aspergillose sinusienne invasive pseudo tumorale: à propos de deux cas.

INTRODUCTION: Pseudo-tumoral fongal rhinosinusitis is a rare and benign illness due to saprophyte germ, Aspergillus flavus. OBSERVATION: We reported two cases of invasive pseudo-tumoral fongal rhinosinusitis. CT scan helped with diagnosis and allowed for extension assessment. Complete surgical excision was done through external approach. Bacteriological examination evidenced the germ. DISCUSSION: Pseudo-tumoral invasive fongal rhinosinusitis remains a potentially serious pathology because of its local aggressiveness and its multiple extensions.

[Nondermatophytic and noncandidal fungi isolated in Le Dantec University hospital of Dakar in 2014: Epidemiological, clinical and mycological study]. / Champignons non dermatophytiques et non candidosiques isolés au CHU Le Dantec de Dakar en 2014 : étude épidémiologique, clinique et mycologique.

In recent years, the incidence of superficial fungal infections involving nondermatophytic and noncandidal fungi increased considerably. The objective of this work was to analyze the epidemiological, clinical and mycological fungal infections due to nondermatophytic and noncandidal fungi diagnosed in the laboratory of parasitology-mycology of Le Dantec hospital in Dakar. With a retrospective study of the various cases of nondermatophytic and noncandidal fungi isolated in the laboratory of parasitology-mycology during the period of November 2013 to December 2014, we collected 22 cases of infections in 11 men and 11 women; age ranging from 17 to 75 years with a mean of 45.3 years (sex ratio=1): eight cases of intertrigo, seven cases of onychomycosis, four cases of palmoplantar keratoderma (KPP), a case of onychomycosis associated with interdigital intertrigo, a case of infectious myositis and one case of African histoplasmosis. We have isolated and identified a total of 22 nondermatophytic and noncandidal fungi: ten Fusarium, five Trichosporon, two Chrysosporium, two Geotrichum, one Rhodotorula, one Neoscytalidium dimidiatum and one Histoplasma capsulatum var. duboisii. So we are seeing the emergence of nondermatophytic and noncandidal increasingly isolated from superficial and local lesions. These fungi, generally contaminants or commensal, cause a problem regarding their direct involvement in pathological processes in which they are isolated. So we should respect the recommendations proposed for their involvement in pathological processes and, by a collaboration between clinician and biologist, demonstrate their real involvement through effective, targeted treatment.

[Primitive neuroectodermal tumor of the vagus nerve]. / Tumeur neuroectodermique primitive du nerf vague.

Primitive neuroectodermal tumors are a rare type of malignant neuroectodermal tumor that is very aggressive. Cervicofacial location is rare, even exceptional. We report a case of a 4-month-old male infant, referred from the pediatric clinic for severe supralaryngeal dyspnea, a firm mass under the left mandibular angle, mobile and extended to the parotid area, painful, with a curve of the left side wall of the oropharynx. Cervical computed tomodensitometry showed a well-limited mass in the carotid area, enhanced by the contrast product. A vascularized mass, which had developed at the expense of the vagus nerve, was removed surgically. Histology found a primitive neuroectodermal tumor.

Management of acquired cholesteatoma in children: a 15 year review in ENT service of CHNU de FANN Dakar.

OBJECTIVES: To analyze the epidemiology, diagnosis, management and the prognosis of cholesteatoma of the middle ear in children. METHODS: This was a retrospective study of 15 years (from 01 January 1995 to 31 December 2009) for patients aged 0-15 years admitted in ENT ward of FANN hospital for chronic otitis media complicated with cholesteatoma The parameters studied were epidemiology, clinical presentation, disease progression and management. RESULTS: Sixty-six participants were included. We noted a slight male predominance with a sex ratio of 1.44. The average mean age was 10 years. Most patients presented with signs of complications (69.7%) and mastoiditis was the most common complication (63.6%). The otorrhea was noted in almost all patients: n = 64 (97%) and deafness in 49 patients (74, 2%). There was a slight predominance of cholesteatoma on the right side (51.5%). Schuller's view of the mastoid cells was done in 21.2% of patients (n = 14) and showed sclerotic mastoid air cells for all them. Eighty-two percent (82%) of patients presented with conductive hearing loss. A radical mastoidectomy was performed in 66.7% and modified radical mastoidectomy in 33.3% of cases. Mean follow-up was 6 months. Recurrence of cholesteatoma was noted in 13% of cases. CONCLUSIONS: ENT ward of Hospital Fann is one of the two centers in Senegal where cholesteatoma of the middle ear are treated. This low number of cholesteatoma in children in a developing country is in relation to the fact that patients only present when complications develop: 70% of cases. The reason for this in our setting include insufficient human and manpower resources necessary for prompt management of the disease and also lack of awareness among the populace. In these settings we advocate canal wall down mastoidectomy (radical or modified radical) as the treatment of choice.

A case of cervical Pott's disease revealed by parapharyngeal abscess.

INTRODUCTION: We report a case of cervical Pott's disease revealed by parapharyngeal abscess. CASE REPORT: A seven-year-old boy was admitted with a three-week history of painful fluctuating left lateral cervical swelling, associated with night sweats. Examination found trismus, through which a lateral pharyngeal bulge could be observed. Incision and drainage of the abscess on a combined cervical-oropharyngeal approach was performed under general anesthesia, associated to non-specific antibiotherapy by parenteral route. Bacteriology was negative. After one week of antibiotherapy, fever persisted with onset of torticollis. A diagnosis of tuberculosis was considered. Tuberculin skin test was positive at 16.5 mm. A second sample by pharyngeal aspiration showed caseous pus with acid-fast bacilli. Cervical spine CT found a retrostyloid abscess with atlantoaxial lysis. Cervical Pott's disease complicated by Grisel syndrome was diagnosed. Antituberculosis therapy was initiated. Results at five months' follow-up were satisfactory. DISCUSSION/CONCLUSION: Parapharyngeal abscess with an etiology of Pott's disease is rare. Modern imaging is highly contributive to diagnosis and follow-up of lesion regression under treatment.

[Study of two cases of virological failure antiretrovirals in the Institute of Social Hygiene (ISH) of Dakar]. / Etude de deux cas d'echec virologique aux antiretroviraux a L'Institut D'Hygiene Sociale (IHS) de Dakar.

CONTEXT: The long term treatment of VIH/SIDA puts down majors risks among which the happening of virological failure or resistance to the anti-retroviral treatment at the patient. OBJECTIVE: To study the cases of resistance to antiretroviral to a cohort of 70 patients of the social hygiene of Dakar. METHOD: This is a retrospective study of the medical records of 70 patients followed in the social hygiene of Dakar during 24 mouths. Data were gathered with the help of form having following variables: The period of meadow inclusion; The period of inclusion; The period of rebound virological; The rate of CD4 count; The viral load and weight of patients. RESULTS: Average of age in inclusion is of 47.5 years with a sex ratio of the women HIV 1 was dominant. Two cases of virological failure were found or (2.8%). The patient 1 was the stade II of the classification of the with as therapeutic class 2INTI + 2 INNTI. It was in stage asymptomatic with as therapeutic protocol DDI + 3TC + NVP. The patient 2 was at the stade III of the whom that is to say at the stade in AIDS with as therapeutic class: 2INTI + 1IP with the protocol of treatment DDI + 3TC +IND. CONCLUSION: The virological failure to the newly infected persons noticed more and more in the world poses a problem of public health because it constitutes a threat for the success of the programs of treatment of the HIV/AIDS.

Osteolipoma: an unusual tumor of the parotid region.

PURPOSE OF STUDY: Oncology of the parotid region is rich and varied, like its components. During his career, the ENT surgeon may come across such an exceptional tumor as osteolipoma. The aim of this study was to describe the rarity and the etiopathogeny of osteolipoma with parapharyngeal location. PATIENTS AND METHOD: We had the opportunity to find this uncommon tumor in a 21-year-old female patient. The mass located in the parotid region was hard, barely mobile and at first looked like a parotid tumor. Total parotidectomy with facial nerve preservation was performed. It revealed a stony and dented tumor inside the internal lobe of the parotid located in the parapharyngeal space between the vertical portion of the mandible anteriorly and the styloid apophyse posteriorly. Macroscopic examination of the piece evidenced a lipomatous mass with hard as bone nodes in its middle. Histology revealed an osteolipoma. CONCLUSION: A review of the literature shows the uncommon occurrence of this type of tumor. A few rare cases were reported among which two involving the parapharyngeal space.

[Contribution of the musculocutaneous flap of pectoralis major in head and neck oncology: 26 observations in Senegal]. / Apport du lambeau musculo-cutané du pectoralis major en carcinologie cervico-faciale: 26 observations au Sénégal.

INTRODUCTION: The pectoralis major musculocutaneous flap constitutes a significant advance in cervicofacial carcinology. At our institution, it has allowed most surgical problems to be resolved in a single-stage procedure. The objective of this study was to report our experience with this flap. PATIENTS AND METHODS: This retrospective study includes 26 cases observed over a 10-year period (January 1994-December 2003). The parameters studied were clinical and paraclinical. All patients included in this study received a pectoralis major musculocutaneous flap. Patients treated using another type of flap were not included. RESULTS: Mean patient age was 51 years (range, 20 to 74). The sex ratio was 12 (24 men and 2 women). At the time of admission, 73% of patients showed marked impairment of general condition. In 21 patients (81%), the effect of the pectoralis major musculocutaneous flap was observed immediately after surgery unlike pharyngostome (19%) in which the flap is used in a second stage procedure. With a mean follow-up of 7 years, failure has been observed in 4 cases (15%). CONCLUSION: The pectoralis major musculocutaneous flap is an excellent tool for cervicofacial reconstruction after carcinological exeresis. It reduces the duration of hospitalization. Acquiring proper flap harvesting technique is an important factor in improving outcome.