Subject(s)
Melanoma/therapy , Metronidazole/therapeutic use , Radiation-Sensitizing Agents/therapeutic use , Radiotherapy, High-Energy , Skin Neoplasms/therapy , Adult , Aged , Combined Modality Therapy , Female , Humans , Male , Melanoma/radiotherapy , Melanoma/surgery , Middle Aged , Skin Neoplasms/radiotherapy , Skin Neoplasms/surgeryABSTRACT
This review of data from pathology departments in the town of Obninsk has shown that over the last 20 years the most frequent causes of death, among males and females alike, were cardiovascular diseases (44%), with malignant neoplasms ranking second (30%) and causing almost twice as many deaths among males as among females. From 63% to 85% of deaths due to malignancy were from epithelial tumors, particularly of the stomach and lungs. A steady increase in the volume of autopsy material and especially of material from intravital morphologic examinations was apparent, with a tendency to a rise in the proportion of biopsy specimens relative to operative specimens, although the latter still predominate.
Subject(s)
Cardiovascular Diseases/pathology , Hospital Departments , Neoplasms/pathology , Pathology Department, Hospital , Adolescent , Adult , Age Factors , Aged , Cardiovascular Diseases/mortality , Child , Female , Humans , Male , Middle Aged , Neoplasms/mortality , Russia , Sex Factors , Urban PopulationSubject(s)
Enterocolitis/complications , Intestinal Obstruction/etiology , Intestine, Small/radiation effects , Radiation Injuries/complications , Adult , Enterocolitis/etiology , Enterocolitis/pathology , Female , Gamma Rays/adverse effects , Humans , Intestinal Obstruction/pathology , Radiation Injuries/etiology , Radiation Injuries/pathology , Radiotherapy/adverse effects , Time FactorsABSTRACT
Secondary tumors developed in the zone of exposure fields in 6 patients treated with radiation for different malignancies. Tumors appeared, on the average, 12 years after radiotherapy.
Subject(s)
Neoplasms, Radiation-Induced/etiology , Radiotherapy/adverse effects , Sarcoma/etiology , Aged , Female , Humans , Middle Aged , Neoplasms/radiotherapySubject(s)
Hodgkin Disease/complications , Splenic Rupture/etiology , Adult , Humans , Male , Rupture, Spontaneous , Splenic Rupture/diagnosisABSTRACT
The writers examined histologically and histochemically the melanomas removed in 40 patients, subjected to general and local hyperthermia associated with radiation and chemotherapy. In such cases it was found that melanoma tissues exhibit grave destructive changes characterized by the morphological features, which are manifested by microcirculatory disorders in the tumor and metastases and are associated with extensive injuries of the neoplastic tissue.