ABSTRACT
The content of rheumatoid factor and the levels of IgA, IgM, IgG in patients with different degrees of sensitization to Borrelia garinii antigens were studied. The titer of rheumatoid factor was found to increase in accordance with the growth of the levels of anti-Borrelia antibodies. A rise in the concentration of serum immunoglobulins simultaneously with the development of Borrelia infection was registered. The mechanisms of autoimmunization are discussed, taking into account the known biological properties of the causative agent of Lyme disease.
Subject(s)
Antibodies, Bacterial/blood , Borrelia burgdorferi Group/immunology , Lyme Disease/immunology , Rheumatoid Factor/blood , Adult , Antibodies, Bacterial/biosynthesis , Autoimmunity , Humans , Immunoglobulin A/blood , Immunoglobulin G/blood , Immunoglobulin M/blood , Lyme Disease/blood , Middle Aged , Rheumatoid Factor/biosynthesisABSTRACT
The content of rheumatoid factor and serum IgA, IgM and IgG in patients with different degree of sensitization to B. garinii antigens is evaluated. An increase in the titer of rheumatoid factor in patients with a high content of antibodies to Borrelia was established. In addition, an increased concentration of serum immunoglobulins in the presence of Borrelia infection was registered. The mechanisms of autoimmune reactions are discussed, proceeding from the biological properties of the causative agent of Lyme disease.
Subject(s)
Antigens, Bacterial/immunology , Arthritis, Rheumatoid/etiology , Autoantibodies/blood , Borrelia burgdorferi Group/immunology , Lyme Disease/complications , Rheumatoid Factor/blood , Adult , Arthritis, Rheumatoid/blood , Borrelia burgdorferi Group/isolation & purification , Humans , Immunization , Immunoglobulin A/blood , Immunoglobulin G/blood , Immunoglobulin M/blood , Lyme Disease/blood , Lyme Disease/immunology , Middle AgedSubject(s)
Chlamydia Infections/complications , Mycoplasma Infections/complications , Respiratory Tract Infections/microbiology , Chlamydia Infections/immunology , Humans , Immunoglobulin A/immunology , Immunoglobulin G/immunology , Immunoglobulin M/immunology , Mycoplasma Infections/immunology , Respiratory Tract Infections/immunologyABSTRACT
It was investigated the influence of food diet supplements with chromium on dynamic of glycaemia, lipid profile, blood pressure and weight in type 2 diabetic patients. Traditional hypocaloric diet was supplemented with chromium-spirulina (50 mcg chromium per day). The results investigations indicated that a chromium-enriched diet has beneficial effects on basal and postprandial glycaemia, the content of cholesterol and triglycerides in serum in compared with a traditional hypocaloric diet.
