ABSTRACT
The immediate and short-term results of radiotherapy of brain stem tumors in 24 children were evaluated. All the patients were able to sustain treatment due to adjuvant support with dehydrating and hormonal drugs, and beneficial clinical effect was recorded in 80%. However, MRT showed no decrease in tumor size. Tumor growth relapsed 3-8 months after radiotherapy. Although total dose ranged 60-72 Gy in 19 patients, there was clinical evidence of radiation injury.
Subject(s)
Brain Stem Neoplasms/radiotherapy , Adolescent , Child , Child, Preschool , Female , Humans , Male , Radiation Injuries/etiology , Radiotherapy/adverse effects , Radiotherapy Dosage , Radiotherapy, Adjuvant , Survival Analysis , Time Factors , Treatment OutcomeABSTRACT
The efficacy of combined treatment of 176 children of different age has been analyzed. All the children suffered from Hodgkin's disease which was treated according to protocols COPP, MOPP, DVPP, +radiotherapy, maintenance chemotherapy. The response to the treatment got worse at the age of prepuberty and puberty, e. g. younger children had recurrences in 19.2% of the cases, adolescents had in 33.3%. The latter more frequently died of the malignancy progression. It is concluded that children older than 13 years are at greater risk of bad Hodgkin's disease outcomes and need more intensive treatment programs.
Subject(s)
Hodgkin Disease/therapy , Adolescent , Age Factors , Child , Child, Preschool , Combined Modality Therapy , HumansABSTRACT
Aggregation of erythrocytes was determined in 50 patients with angina pectoris and myocardial infarction and in 20 subjects of the control group by rheoscopy after Schmid-Schoenbein. It is shown that in patients with ischemic heart disease aggregation of erythrocytes is considerably increased and the hydrodynamic strength of the aggregates is greater. The erythrocyte aggregation curve is some patients with ischemic heart disease was of a biexponential character in distinction to that in subjects of the control group, which was of the monoexponential type. It was found that the increase in the strength of the erythrocyte aggregation and in the rate of aggregate formation was due to fibrinogen and its complex compounds with decomposition products.
