ABSTRACT
Bacteriological tests on feces of patients with ulcerative-hemorrhagic colitis, in exacerbation, were carried out. The same patients were dynamically followed up as regards clinical picture and paraclinical indices, rectoromanoscopy include. Quantitative and qualitative analysis of the fecal microflora was made according to the following indices: total number of mesophili aerobic microorganisms, coli-bacteria, proteus, enterococci, staphylococci, Salmonella-bacteria. The pure cultures isolated were tested according to 30 biochemical indices, their precise classification position being determined on that base. The production of the following enzymes was studied in the cultures isolated: protease, oxyreductase -- catalase and peroxidase, aminotransferase -- COT and GPT; phosphatase -- acid and alkaline, disaccharidase and urease. The data obtained from the bacteriological studies were compared with those of a control group of healthy subjects. Elevated enzyme constellation was found among the patients with exacerbated ulcerative-hemorrhagic colitis.
Subject(s)
Colitis, Ulcerative/microbiology , Gastrointestinal Hemorrhage/microbiology , Adult , Enzyme Activation , Feces/enzymology , Feces/microbiology , Humans , Middle Aged , Proteus/enzymology , Proteus/isolation & purification , Recurrence , Salmonella/enzymology , Salmonella/isolation & purification , Staphylococcus/enzymology , Staphylococcus/isolation & purificationABSTRACT
A patient with repeated hemolytic episodes since early childhood of undistinguished etiology is described. The patient was three times admitted to hospital--infectious and internal diseases clinics on the occasion of the manifested hemolytic-icteric syndrome. The clinical, biochemical, genealogical and other investigations carried out, confirmed the presence of G-6-PD deficiency. That genetic effect was found in 6 of all 17 subjects, examined of the family. The patient had inherited the genetic defect from his mother. The studies in accordance with WHO programme, revealed that a G-6-PD, type Corinth variant, was concerned. The male-patient, presented by us is of particular interest in a clinical and differentiation diagnostic aspect.
Subject(s)
Glucosephosphate Dehydrogenase Deficiency/genetics , Adult , Dyspepsia/pathology , Glucosephosphate Dehydrogenase Deficiency/pathology , Humans , Jaundice/pathology , Male , Mutation , PedigreeABSTRACT
The intestinal dipeptidase and disaccharidase activities were investigated in 120 male albino rats of the Wistar strain after administration of 21 mumol.kg-1 body weight phosalone, 14.8 mumol.kg-1 body weight lindane and 10.5 mumol.kg-1 body weight phosalone combined with 7.4 mumol.kg-1 body weight lindane. The dipeptidase activity under the effect of these comparatively low doses of pesticides reveals slightly to moderate changes. The activity of intestinal disaccharidases after a 90-day phosalone and lindane treatment is markedly decreased, particularly that of sucrase. The mechanism of these changes remains unknown.
