[The relevance of Candida spp. in chronic periodontal disease]. / Vyiavlenie drozhzhepodobnykh gribov roda u patsientov s khronicheskim generalizovannym parodontitom.

The aim of the study was to assess the correlation of Candida spp. incidence in periodontal tissues with various clinical manifestations of chronic periodontal disease (CPD). Ninety patients with CPD were included in the study in which Candida spp. was evaluated in periodontal pockets content and gingival biopsy material. In severe CPD more Candida spp. were seen in gingival biopsy than in periodontal pockets (p=0.0006). Candida spp. incidence and quantity correlated directly with the disease grade showing incidence increase from 40 to 73.3% and quantity increase from 0.8±0.18 до 3.6±0.49 lg CFU/ml in light and severe CPD, correspondingly Candida spp. had statistically significant association with cyanotic gingival color (p=0.0018), tongue plaque and swelling (р=0.0042), lip exfoliation (р=0.0030), periodontal pockets depth >5 mm (р=0.0030), oral mucosa hyperemia (р=0.0157), alveolar bone destruction >1/2 of root length (р=0.0157). These data prove the relevance of Candida spp. and mycological assessment of gingival biopsy in CPD patients.

[Clinical and microbiological rationale for laser removal of infected epithelia in patients with periodontitis].

The aim of the study was to identify clinical microbiological criteria for the necessity of removal of infected epithelium in the periodontal pocket in patients with periodontitis. A total of 90 patients diagnosed with periodontal disease of varying severity were assessed. Clinical examination of the patients was performed, including the definition of index numbers and microbiological diagnosis of the content of periodontal pocket and periodontal tissues by biopsy culture seeding. Epithelial integration of lactobacilli and bifidobacteria was established, indicating the need for a differentiated approach to the removal of gingival epithelium. Diagnostic criteria for deepitalization was identified: marked inflammatory response of periodontal tissues, characterized by performance indexes PMA > 50%, Mulleman > 1.5, Svrakov > 2.7, correlated with the degree of contamination biopsy 4IgKOE/ml and Candida spp. 2IgKOE/ml.

[Mass spectral analysis of water in intact dental enamel in subjects with different caries resistance]. / Mass-spektral'nyi analiz vody intaktnoi zubnoi émali u lits s razlichnym urovnem rezistentnosti k kariesu.

Mass-spectrum analysis of specimens of intact dental enamel of subjects with different caries resistance was carried out. Products of gaseous phase released during constant heating of enamel were analyzed. Water mass spectrum was distinguished to be used in thermal programmed desorption analysis for the study of the organic constituent of dental enamel.

[Study of thermal stability of intact dental enamel in subjects with different levels of caries resistance]. / Issledovanie termoustoichivosti intaktnoi zubnoi émali u lits s razlichnym urovnem rezistentnosti k kariesu.

Thermal stability of intact dental enamel was compared by combined TH-DTH-DTA analysis in subjects with different caries resistance. Thermal stability was found to depend on the presence and degree of organic and inorganic components stability. The content of organic phase virtually was virtually the same in samples with different levels of resistance, which was confirmed by the fact that oxidative destruction of organic substances in intact dental enamel took place at the same temperatures in samples of all resistance levels.

[Characteristics of dental enamel and its resistance to caries]. / Teksturnye kharakteristiki émali zuba i ee rezistentnost' k kariesu.

Systematical research of basic texture characteristics (specific surface area, specific volume and size of micro-, meso- and macropores, porosity) of intact dental enamel of persons with various degree of resistance to caries has been performed using methods of adsorption and Hg-porosimetry. Studied objects have been shown to be small-porous (total porosity epsilon = 4-6%), roughly-dispersed (specific surface S6ET = 0.7-1.5 m2/g) materials. Regularities of changes of specific surface and porous structure in researched samples have been established. More mesoporous enamel structure has been shown to form in the series of samples varying from high level of resistance to very low level. Meanwhile intact dental enamel has the same degree of macroporosity irrespective of the level of its resistance to caries. Micropores within the samples have been established to be heterogenous and their volume to be very insignificant (2-4 x 10(-9) m3/g). Substantiation of various degree of resistance of intact dental enamel to carious process has been suggested within the framework of structurally-geometrical approach.