Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Language
Publication year range
1.
RSC Med Chem ; 11(5): 597-601, 2020 May 01.
Article in English | MEDLINE | ID: mdl-33479662

ABSTRACT

Modified carbocyclic nucleosides (4a-g) constituting 7-deazapurine, 4'-methyl, exocyclic double bond and 2',3'-hydroxy were synthesized. NOE and X-ray studies of 4c confirmed the α-configuration of 4'-methyl. The anti-HBV assay demonstrated 4e (IC50 = 3.4 µM) without notable cytotoxicity (CC50 = 87.5 µM) as a promising lead for future exploration.

SELECTION OF CITATIONS
SEARCH DETAIL
...