[The clinico-physiological manifestations and the pathophysiological mechanisms of respiratory failure in tuberculosis and nonspecific lung diseases]. / Kliniko-fiziologicheskie proiavleniia i patofiziologicheskie mekhanizmy dykhatel'noi nedostatochonosti pri tuberkuleze i nespetsificheskikh zabolevaniiakh legkikh.

One hundred and forty-seven patients with tuberculosis and nonspecific lung diseases underwent comprehensive clinical and physiological studies at rest and during exercises of 0.5 and 1.0 W per kg body weight of the examinee. Respiratory failure was found in more than half of them, which was due to pulmonary insufficiency in the vast majority of cases and due to cardiopulmonary insufficiency in much fewer cases. In the two respiratory failures, impaired mechanics of respiration and distributive function of the lung play the leading role in the development of respiratory function. The contribution of the impaired diffusion capacity of the lung as a cause of arterial hypoxemia increases with the severity of diffusive disorders and during exercises.