1.
Angew Chem Int Ed Engl
; 45(8): 1302-5, 2006 Feb 13.
Article
in English
| MEDLINE
| ID: mdl-16425309
2.
Org Lett
; 7(7): 1227-9, 2005 Mar 31.
Article
in English
| MEDLINE
| ID: mdl-15787473
ABSTRACT
[reaction: see text] The first enantioselective synthesis of (+)-trans-195A is described. The structure has been constructed by ring-rearrangement metathesis (RRM) and zirconium-mediated Negishi-coupling, used for the first time to prepare 6,6-membered heterocycles, as key steps. By comparison of the synthesized material with the isolated natural product, the absolute configuration of natural trans-195A was determined to be (2R,4aS,5R,8aS)-(-).
