ABSTRACT
BACKGROUND: Here we report the application of optical frequency domain imaging (OFDI), a new optical coherence tomography device, for intravascular visualization in the treatment of a recanalized unruptured internal carotid artery aneurysm that was treated initially by stent-assisted coil embolization. CASE DESCRIPTION: OFDI revealed malapposition of the stent and lack of neointimal growth at the aneurysm neck, which was treated by deployment of a Pipeline Embolization Device to overlap the stent. An angiogram performed 1 year after the procedure revealed perfect healing of the aneurysm, and OFDI clearly demonstrated good stent apposition and total endothelialization over the aneurysm neck. CONCLUSIONS: OFDI/OCT appears to be a useful diagnostic tool for evaluating stent-strut apposition over the vessel wall and the grade of neointimal endothelialization across the neck of the aneurysm in aneurysmal recanalization.
Subject(s)
Carotid Artery, Internal/diagnostic imaging , Intracranial Aneurysm/diagnostic imaging , Intracranial Aneurysm/therapy , Neuroimaging/methods , Tomography, Optical Coherence/methods , Carotid Artery Diseases/diagnostic imaging , Carotid Artery Diseases/therapy , Embolization, Therapeutic/methods , Endovascular Procedures/methods , Female , Humans , Middle Aged , Neuroimaging/instrumentation , Stents , Tomography, Optical Coherence/instrumentationABSTRACT
Given that exposure to captive wild animals at circuses or zoos can be a source of zoonotic infection, a case and control study was carried out with a collection of exotic fowl at a zoo in Bogotá, Colombia. The presence of Mycobacterium avium-II was directly related to the death of birds kept in the original enclosure, and of 50% of a group of sentinel birds. Failure to detect the organism in a control group of birds outside the enclosure indicated that the infection was limited to the original enclosed area. We demonstrated that M. gordonae-IV was disseminated in all organs from 1 bird with macroscopic granulomatous lesion, a finding which has not been reported previously. We emphasize the importance of establishing handling norms to reduce the risk of zoonotic transmission.