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Gan To Kagaku Ryoho ; 32 Suppl 1: 62-4, 2005 Dec.
Article in Japanese | MEDLINE | ID: mdl-16422491

ABSTRACT

We would like to present a case report on how we managed to reduce an adverse effect of chemotherapy, specifically vomiting and nausea with a sedative agent diazepam, when a patient was intravenously injected with chemotherapeutic agents at the outpatient department. The patient was a 39-year-old female who experienced total hysterectomy and bilateral oophorectomy due to ovarian ca. (stage III) on May 29, 2002. She used to have complained of severe vomiting whenever undergoing 4-day inpatient chemotherapies every month from June 2002 to April 2003. In the last chemotherapy, she suffered vomiting prior to a day before the infusion and after 5 days of the infusion. Because of her experience, the patient refused to undergo the following chemotherapy. Based on discussions with her, use of sedatives was chosen to relieve vomiting. Due to relief of stress, the patient slept and relaxed by means of a sedative effect during and after administration of chemotherapy. Since the reduction of vomiting, she has been accepting further chemotherapies.


Subject(s)
Antiemetics/therapeutic use , Diazepam/therapeutic use , Hypnotics and Sedatives/therapeutic use , Ovarian Neoplasms/psychology , Vomiting, Anticipatory/drug therapy , Adult , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Cisplatin/adverse effects , Female , Humans , Outpatients , Ovarian Neoplasms/drug therapy
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