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Boll Chim Farm ; 141(3): 197-201, 2002.
Article in English | MEDLINE | ID: mdl-12197418

ABSTRACT

New 3-(2,3-dimethyl-1-phenyl-4-pyrazolon-5-yl)-4-thiazolidones were synthesized. The structure of substances was supported by UV- and 1H-NMR spectra. Some compounds were tested in vivo for their antiinflammatory activity. Were confirmed previous results about structure-activity relationships.


Subject(s)
Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis , Anti-Inflammatory Agents, Non-Steroidal/pharmacology , Thiazoles/chemical synthesis , Thiazoles/pharmacology , Animals , Edema/chemically induced , Edema/prevention & control , Female , Indicators and Reagents , Magnetic Resonance Spectroscopy , Male , Rats , Spectrophotometry, Ultraviolet
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