ABSTRACT
For the first time in Bulgaria and maybe in the world is reported very good therapeutic effect of the application of external drainage of the thoracic duct with and without lymphosorption in two consecutive cases of phalloid mushroom poisoning. Concrete indications are suggested for application of the method in this type of poisoning - in the late endotoxic phase of the poisoning when all other methods have been used with no effect.
Subject(s)
Lymph , Mushroom Poisoning/therapy , Sorption Detoxification/methods , Thoracic Duct/surgery , Amanita , Child , Child, Preschool , Coma/etiology , Coma/therapy , Combined Modality Therapy , Drainage/methods , Emergencies , Female , Humans , Mushroom Poisoning/complicationsABSTRACT
Plasma toxicity and plasma exchange efficacy were studied in two groups of patients: I gr.--8 patients with various degree of disturbed renal function who did not need hemodialysis treatment; II gr.--9 patients treated by periodic hemodialysis. A biologic toxicity test was used together with the clinical, immunologic and biochemical indices as a criterion for plasma exchange efficacy. The test gives direct information for the total plasma toxicity which is of great advantage and helps in the decision for another plasma exchange.
Subject(s)
Kidney Diseases/therapy , Plasma Exchange , Animals , Biological Assay/methods , Chronic Disease , Evaluation Studies as Topic , Humans , Kidney Diseases/immunology , Paramecium/immunology , Plasma/immunology , Plasma Exchange/instrumentation , Plasma Exchange/methods , Renal DialysisABSTRACT
A case with Wegener's granulomatosis in a young woman is described. The diagnosis was made after extirpation and histological investigation of granuloma tissue from the nasal concha and by needle renal biopsy. A successful treatment was carried out with plasmapheresis, hemodialysis and immune-suppressors, the acute paroxysm being coped as well as the developed acute renal insufficiency. After each plasmapheresis a considerable reduction of the circulating immune complexes was established. After a remission of 9 months the patient developed a stage of terminal chronic renal insufficiency and was subjected to chronic dialysis with good rehabilitation.
