[State of ENT organs in patients with sleep apnea syndrome and methods of surgical treatment]. / Sostoianie LOR-organov u bol'nykh s sindromom apnoé vo sne i metody khirurgicheskogo lecheniia.

Night snoring and cessation of breathing for 20-120 min should be considered as potentially lethal condition as it is associated with a rise in arterial, intracranial and intrathoracic pressure. Snoring apnea may be of central, peripheral and mixed origin. Peripheral and mixed apnea is treated by ENT surgeon and neuropathologist.

[Determination of fructosamine in the early diagnosis of disorders of carbohydrate metabolism]. / Opredelenie fruktozamina v rannei diagnostike narushenii uglevodnogo obmena.

Blood serum fructosamine level were measured on an empty stomach in 97 normal subjects and subjects with various disorders of carbohydrate metabolism (the so-called "pre-diabetes" and changed glucose tolerance) in order to elucidate the significance of this factor as a marker of such disorders. Fructosamine concentrations were for the first time measured in children whose parents suffered from insulin-dependent or noninsulin-dependent diabetes mellitus. The content of fructosamine on an empty stomach was found to depend on the degree of carbohydrate metabolism disorders, increasing with the progress of these disorders. The findings permit a conclusion on the possibility of using fructosamine as a marker for the diagnosis of "pre-diabetes" in subjects with its levels of 2.5 to 2.99 mmol/l and of disordered glucose tolerance in those with its levels over 3 mmol/l and glucose level on an empty stomach no more than 6 mmol/l.

[Minidiab test to assess the functional state of pancreatic beta-cells in the children of diabetics]. / Proba s minidiabom v otsenke funktsional'nogo sostoianiia beta-kletok podzheludochnoi zhelezy u potomkov bol'nykh sakharnym diabetom.

The levels of glucose, insulin, and C-peptide in the blood serum were measured in 38 subjects with normal and impaired glucose tolerance whose parents suffered from insulin-dependent and noninsulin-dependent diabetes mellitus (IDDM and NIDDM, respectively) and in 12 normal subjects without hereditary aggravation for diabetes mellitus in order to specify the peculiarities of development of diabetes mellitus of various types. Reliably increased levels of glucose, insulin, and C-peptide on an empty stomach and absence of adequate secretion of insulin and C-peptide in response to stimulation with 5 mg of minidiab, expressed by a later and less manifest release of insulin and C-peptide, were observed in the test group, in contrast to healthy controls. The detected changes augment with the progress of carbohydrate metabolism disorders, being more marked in the subjects whose parents suffered from IDDM. The findings permit a conclusion that function of the insular system is changed during early disorders of carbohydrate metabolism in subjects whose parents suffered from both forms of diabetes mellitus. Minidiab test is recommended to specify the function of the pancreatic insular system.