Modern approaches to treatment of pseudomonas aeruginosa ventilator-associated pneumonia (literature review).

OBJECTIVE: Introduction: Nowadays anti-microbial therapy of ventilator-associated pneumonia caused by is one of the most topical issue as a consequence of widespread multiresistant strains of causative agent and their biological peculiarity of actively formation of resistance to new antibacterial drugs. The aim is to describe modern approaches to therapy of ventilator-associated pneumonia causative agent of which is presented by Pseudomonas aureginosa . PATIENTS AND METHODS: Materials and methods: An analysis and summing up of results of scientific investigations described in medical publications concerning the issues of therapy of ventilatorassociated pneumonia caused by Pseudomonas aureginosa was done. CONCLUSION: Conclusions: Despite the development of modern approaches to anti-microbial therapy of ventilator-associated pneumonia caused by Pseudomonas aeruginosa, which are also concerned with such controversial issues as correct choice of antibacterial drug, its optimal dose, and duration of this therapy, the problem of treatment of hospital-acquired infections of respiratory airways caused by Pseudomonas aeruginosa has been discussable yet and requires the further study.

Modern approach to the problem of pertussis.

OBJECTIVE: Introduction: Recently, there has been a tendency to increase the incidence of pertussis in many countries of the world and this disease in these countries is among 10 most serious causes of death in young children. The aim of the work - is to analyze specialized scientific literature for generalization of data and present a modern look at questions of etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, treatment and immunoprophylaxis of pertussis. PATIENTS AND METHODS: Materials and methods: Available scientific sources over the past years, devoted to the problem of pertussis are studied by the methods of overview, system and content analysis. RESULTS: Review and conclusions: The main questions of pertussis are outlined. Timely diagnosis, treatment and immunoprophylaxis allow adjusting the actions of doctors to solve the issues of the decrease of the incidence of pertussis. This is greatly helped by modern guidelines for the management of patients with this pathology.