Residential swimming pools maintenance under an environmental perspective.

Swimming pools provides various benefits for users, but their owners need to carry out constant maintenance to ensure water quality and user safety. This paper goal was to assess the maintenance process of residential swimming pools, through Life Cycle Assessment based on NBR ISO 14040:2014 and NBR 14044:2014. The standard steps were followed and primary data on materials and quantities for the treatments were collected during 2022. The purchase costs of the treatment process were obtained, which based the cost analysis. The Impact Assessment Method used was the ReCiPe Endpoint (H) 2016, which assesses damage across three categories. The water, electricity and hypochlorite production processes were the most impactful in the categories of damage to human health, ecosystems and resources availability. These inputs production have an intense natural resources consumption and causes emissions into the environment. The highest expenses in pool maintenance were associated to human resources (worker) and chlorine purchase, followed by electricity. Scenarios were created to identify feasible changes to reduce the impacts. The waiver of water for replacement in the rainy season had greater potential for reducing impacts than the consumption changes in electricity and chlorine.

Sources of Microplastic Generation in the Environment.

The number of scientific papers on microplastics in the environment has grown exponentially [...].

Evaluation of quality of life (QOL) of young patients with primary hyperhidrosis (PH) before and after endoscopic thoracic sympathectomy (ETS).

BACKGROUND: Primary hyperhidrosis (PH) affects young patients and may cause emotional distress and a negative quality of life (QOL). OBJECTIVE: We sought to evaluate the QOL of children and adolescents with PH treated by endoscopic thoracic sympathectomy. METHODS: A study of 220 patients was performed, based on submitted QOL questionnaires from their first consultation. Patients were evaluated within 1 week and 24 months after surgery. RESULTS: Before endoscopic thoracic sympathectomy, the QOL in relation to PH was declared very poor by 141 patients, and poor by the remaining 79 (P = .552). Postoperative cure was reported in 100% of palmar and axillary PH cases, and in 91.7% of facial PH. After 24 months, the QOL was described as much better by 212 patients, a little better by 6 patients, and 2 patients reported no change. LIMITATIONS: Convenience sampling was used and patients were taken from private practice only, raising the possibility of bias in gathering the data. CONCLUSION: Onset of PH symptoms was mainly before the age of 10 years and substantially affected daily activities. Endoscopic thoracic sympathectomy cured PH and promoted significant improvement in the QOL of these young patients.

Life cycle management in bakeries: a proposed roadmap towards sustainability.

PURPOSE: Some commercial/industrial sectors have increased their interest in sustainability, in some cases changing their business focus, from a profit-centered approach to a more balanced view, including environmental and social factors. It means that the interest in sustainability is increasing. Life cycle management (LCM) is a methodology/concept that can contribute to this paradigm shift. In this research, the potential application of LCM in the bakery segment was investigated, considering the entire value chain related to the sector (inputs, packaging, suppliers, customers, waste management). METHODS: Bakeries were visited, in Teresina, Piauí, Brazil, to learn about the products, services, production processes, and the socio-environmental and economic sustainability practices, aiming at identifying bottlenecks and to propose alternatives based on LCM. Besides the field approach, the study was structured based on the literature that brings the concepts and potentialities of applying LCM in various economic/industrial sectors. The PDCA cycle and the SWOT Matrix were also used to assist the implementation of LCM. A roadmap was proposed aiming at the LCM implementation in bakeries. RESULTS: The results show that although the sector has some environmentally sustainable practices (waste separation, energy savings, reuse of products, inputs purchased locally), the primary intention is to reduce costs and not to mitigate environmental impacts. Regarding social responsibility, they donate bread to institutions. This is an important attitude, but not the only one for fulfilling the social role within the value chain. They do not consider suppliers that show concern for the environment (certified companies), and both marketing and product labels do not evoke these issues too. CONCLUSIONS AND RECOMMENDATIONS: Thus, there is the possibility of implementing LCM in bakeries if there is a concern with sustainable production and consumption. A roadmap for implementing LCM in bakeries was proposed including some steps: mapping the life cycle of products/processes/services associated with the sector; analyzing factors that can influence the actions towards sustainability; disseminating life cycle information to the entire value chain; efficient waste management, including the partnership with recycling companies; and treatment of the collected data and improvement proposal, using management tools such as the PDCA Cycle, the SWOT Matrix, and Environmental, Social and Governance (ESG) aiming at the search for environmental and economic sustainability and social fair alternatives. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11367-021-02008-7.

Selenium status and its relationship with thyroid hormones in obese women.

BACKGROUND AND AIMS: Studies have been conducted with the purpose of elucidating thyroid gland dysfunction in obesity, however the contributing factors for such dysfunction are not yet fully understood. Selenium is notable for its role in thyrocyte protection against oxidative damage and control of thyroid hormone synthesis. In addition, subjects with obesity may exhibit alterations in the selenium homeostasis. Therefore, the present study aimed to examine the selenium status and its relationship with serum thyroid hormone levels in obese women. METHODS: This cross-sectional study included 69 euthyroid women, aged between 18 and 50 years, who were divided in two groups: an obese group (n = 35) and a control group with women of normal weight (n = 34). Selenium intake was assessed by three-day diet records and analyzed using NutWin software version 1.5. Plasma, erythrocyte, and urinary selenium levels were determined using inductively coupled plasma optical emission spectrometry. Testing for thyroid hormones and thyroid autoantibodies was performed based on chemiluminescence. RESULTS: The median dietary selenium content was adequate according to the recommendations, with no statistical difference between groups. Obese women had reduced plasma and erythrocyte selenium levels compared to the control group, although selenium concentration in erythrocytes was adequate within the normal range for both groups. There was no significant difference between the urinary selenium concentrations in the subjects; however, the mineral clearance was higher in the obese group. Free triiodothyronine (fT3) and free thyroxine (fT4) levels were higher in obese women with class II obesity when compared to the control group. There was a negative correlation between plasma selenium and serum fT4 levels. CONCLUSIONS: Obese women showed impairment in selenium homeostasis, however, this fact did not seem to adversely affect thyroid metabolism.

Relationship between selenium status and biomarkers of oxidative stress in Crohn's disease.

OBJECTIVE: Crohn disease (CD) is characterized by chronic intestinal inflammation and various factors involved in its pathogenesis including oxidative stress. The oxidative stress in CD may compromise antioxidant nutrients, such as selenium. The aim of this study was to assess the status of selenium and its relationship with markers of oxidative stress in patients with CD in comparison to controls. METHODS: The study included 47 patients with CD (20 with active disease and 27 in remission) and 25 healthy individuals. Blood samples were collected for the analysis of plasma and erythrocyte selenium concentrations using inductively coupled plasma optical emission spectrometry (ICP-OES). Selenoprotein P (SepP) was evaluated by sandwich enzyme-linked immunosorbent assay, erythrocyte glutathione peroxidase (GPx1) activity was assessed by using an automatic biochemistry analyzer, and the concentration of thiobarbituric acid reactive substances (TBARS) was measured. Comparative analyses were performed using one-way analysis of variance and Tukey's post hoc test. For correlations, Pearson's coefficient test was used. The determinants for CD and lipid peroxidation were indicated by odds ratio. RESULTS: Plasma and erythrocyte selenium levels and SepP concentrations were lower in the CD patient groups than in the healthy group. GPx1 activity and the concentration of TBARS were significantly higher in the CD groups. In the univariate analysis, plasma and erythrocyte selenium and TBARS were associated with CD. CONCLUSION: Patients with CD have impaired selenium status, which is related to the increased oxidative stress observed in these patients.

Saneamento básico como dignidade humana: entre o mínimo existencial e a reserva do possível / Basic sanitation as human dignity: between the minimum existential and the reserve of the possible

RESUMO O caminho que se propõe a percorrer neste trabalho passa pela observação da efetividade dos direitos fundamentais em Teresina, Piauí, tendo o saneamento básico como indicador e destacando o mínimo existencial e a reserva do possível como balizas para o atendimento das demandas no setor. Justificando-se na escassez de recursos financeiros que impede a ampliação de estruturas de esgotamento sanitário, abastecimento de água, drenagem de águas pluviais e coleta de resíduos sólidos, Teresina foi se distanciando do que é considerado como o mínimo existencial em saneamento pela Lei nº 11.445/2007. Reserva do possível não pode ser invocada quando afeta a dignidade humana. A análise documental utilizada nesta pesquisa revelou que o município descumpre a Constituição Federal, por não oferecer condições básicas para evitar que a dignidade da pessoa humana seja desconsiderada nos seus limites territoriais.

ABSTRACT The path that this work proposes to go through involves observing the effectiveness of fundamental rights in Teresina, Piauí, Brazil, introducing basic sanitation as indicator and highlighting the minimum existential and a reserve of the possible as measures to identify the demands of the sector. Sustaining in the scarcity of financial resources that prevent the expansion of structures sanitary sewage, water supply, drainage of rainwater and solid waste collection, Teresina distanced itself from what is considered as the minimum existential in sanitation by the Law no. 11.445/2007. Reserve of the possible cannot be invoked when it affects human dignity. The documentary analysis used in this research revealed that the municipality does not comply with the Federal Constitution, because it does not offer conditions to avoid that the dignity of the human person is disregarded within the territorial limits.

The Quality of Toothbrushing in Children with Intellectual Disabilities Enrolled in an Oral Health Promotion Programme: A Paired Study.

PURPOSE: To assess the quality of toothbrushing of children with intellectual disability (ID). MATERIALS AND METHODS: One hundred thirty-six children, 68 with ID (SG = study group) and 68 non-ID (CG = control group), were paired. Their caregivers completed a questionnaire about socioeconomic and demographic characteristics and another about oral hygiene habits. The toothbrushing technique and position adopted were documented and the duration of the procedure was measured. A modification of the Simplified Oral Hygiene Index (SM-OHI) was used to classify the quality of brushing as: adequate, when all the teeth had SM-OHI 0 or 1; or inadequate, when at least one tooth had SM-OHI 2 or 3. The Kolmogorov-Smirnov test was used to assess the normality of data distribution for age, duration of brushing and SM-OHI. Fisher's exact test and the chi-squared test were applied to assess the association between ID and oral hygiene habits or characteristics of toothbrushing. To compare the duration of brushing groups, the Mann-Whitney test was applied. Student's t-test for independent samples was applied to compare mean MS-OHI. RESULTS: Mothers were the main persons performing children's toothbrushing in SG. They reported a higher daily brushing frequency, longer toothbrushing duration of children in the SG, SG children had lower SM-OHI scores and were thus rated as having adequate toothbrushing, in contrast to the CG (p < 0.001, p < 0.001; p = 0.012; p < 0.001; p < 0.001, respectively). CONCLUSION: Toothbrushing provided by caregivers for ID children was more effective than toothbrushing carried out by non-ID children of the same age and gender.

Desempenho ambiental da produção de ração para frango de corte no Piauí / Environmental performance of feed production for broiler in Piauí state, Brazil

RESUMO Este trabalho teve como objetivos identificar e avaliar os potenciais impactos da produção de ração para frango de corte com a metodologia de avaliação do ciclo de vida. A coleta de dados primários foi realizada em uma cooperativa de avicultores de Teresina (PI) e envolveu a identificação das matérias-primas, além de sua origem e quantidade, e de etapas do processo produtivo. Também, foram utilizados dados secundários do banco de dados Ecoinvent, disponível no software SimaPro, com o qual foi executada a modelagem do processo, pela qual identificamos as entradas e saídas do sistema. O método de avaliação usado foi o ReCiPe Midpoind (H). A caracterização da avaliação de impacto mostrou que os impactos mais significativos estão relacionados à utilização de ingredientes com maior teor de energia e proteína, como milho e soja. Isso se dá em razão dos impactos ambientais negativos associados à produção agrícola desses materiais (dados do Ecoinvent), além do seu transporte entre as fazendas (Uruçuí e Sebastião Leal, região sul do Piauí) e a fábrica de ração (a aproximadamente 520 km de distância de Teresina). Desse modo, são impactos ligados às atividades que ocorrem fora dos limites da cooperativa. Além disso, a utilização da farinha feita com carne e ossos, subproduto oriundo de abatedouros, determinou o aparecimento de impactos ambientais positivos em todas as categorias do método utilizado, com destaque para: eutrofização de corpos de água doce, ecotoxicidade marinha e depleção da camada de ozônio. O reaproveitamento desses subprodutos (farinha feita com carne e ossos) é ambientalmente vantajoso.

ABSTRACT This study aimed to identify and evaluate the potential impacts of feed production for broiler poultry, using the life cycle assessment methodology. Primary data collection was conducted in a poultry cooperative of Teresina, Piauí state, Brazil, and involved the identification of raw materials, as well as their origin and quantity, and the stages of the production process. In addition, we used secondary data from the Ecoinvent database, available in SimaPro software, in which the modeling was performed. The ReCiPe Midpoint (H) was used as the evaluation method. The characterization of the impact assessment showed that the greatest impacts are related to the use of ingredients with high energy and protein content, such as maize and soybeans. This is due to the negative environmental impacts associated with the agricultural production of these materials (Ecoinvent data), as well as the transport between the farms (Uruçuí and Sebastião Leal, Southern Piauí) and the feed factory (approximately 520 km away from Teresina). Thus, these impacts are associated with activities outside the cooperative boundaries. Furthermore, the use of meat and bone meal, a by-product originated from abattoirs, determined the appearance of positive environmental impacts in all categories of the used method, especially: eutrophication of freshwater bodies, marine ecotoxicity and ozone layer depletion. The reuse of these by-products (meat and bone meal) is environmentally advantageous.

Repercussão da iniciação sexual na vida sexual e reprodutiva de jovens de capital do Nordeste brasileiro / Impact of first sexual intercourse on the sexual and reproductive life of young people in a capital city of the Brazilian Northeast

Resumo Objetivou-se analisar a repercussão da iniciação sexual de jovens com antecedentes obstétricos no número de gestações e de parceiros, em Teresina (PI). Trata-se de estudo seccional, realizado com 464 jovens selecionadas por amostragem acidental, que finalizaram uma gravidez quando tinham idade de 15 a 19 anos, no primeiro quadrimestre de 2006, em seis maternidades do município. A coleta dos dados primários ocorreu de maio a dezembro de 2008, no domicílio das jovens, após sua localização nos registros hospitalares. As análises univariada e bivariada se deram por meio de estatística descritiva e Coeficiente de Correlação de Pearson ou Teste t, respectivamente. Empregouse ainda o Teste post hoc de Tukey e as variáveis significativas na análise bivariada (p < 0,05) foram incluídas no modelo de Análise de Variância Multifatorial. A escolaridade (p < 0,001) e a idade da menarca (p < 0,001) influenciaram a idade da iniciação sexual e, esta, por sua vez, apresentou correlação negativa significativa (p < 0,01) com o número de parceiros e de gestações das jovens. Assim, quanto mais cedo ela iniciou-se sexualmente, mais gestações teve até o momento de sua vida reprodutiva, bem como maior número de parceiros sexuais. Portanto, a iniciação sexual precoce repercutiu negativamente sobre estas variáveis.

Abstract This study aimed to analyze the repercussion of first sexual intercourse on the number of pregnancies and partners of teenagers with obstetric history in Teresina (PI), Brazil. This is a cross-sectional study with 464 young women selected by accidental sampling who gave birth at 15-19 years of age in the first four months of 2006 in six maternity hospitals of the municipality. Primary data was collected from May to December 2008 at the participants' homes after tracking them in the hospital medical records. The univariate and bivariate analysis were performed by descriptive statistics and Pearson's Correlation Coefficient Test or T-test, respectively. Tukey's post hoc test was used as post hoc test and significant variables on the bivariate analysis (p < 0.05) were also included in the multifactor analysis of variance model. Schooling (p < 0,001) and menarche's age (p < 0,001) influenced the age of first sexual intercourse and this, in turn, showed significant negative correlation (p < 0.01) with the number of partners and pregnancies of young women. Thus, the earlier the young women start sexual activity, the higher the number of pregnancies and sexual partners until the moment of their reproductive life. Thus, early first sexual intercourse had a negative repercussion on these variables.

Mineral status and superoxide dismutase enzyme activity in Alzheimer's disease.

The study evaluated the dietary intake of zinc and copper, as measured by plasma and erythrocyte concentrations, the Cu/Zn ratio and measure the erythrocyte superoxide dismutase enzyme (eSOD) activity and the relationship between these markers and the degree of dementia in elderly individuals with and without Alzheimer's Disease (AD). A total of 93 elderly people aged 60-94 years were divided into two groups: with AD (n=44) and without AD (n=49). The NINCDS-ADRDA criteria were used for diagnosing AD, and dementia staging was determined using the Clinical Dementia Rating (CDR) scale. The dietary intake of Zn and Cu was obtained from a standard 3-day food record. Plasma and erythrocyte concentrations of the minerals were determined by flame atomic absorption spectrophotometry and by measuring eSOD activity in an automatic biochemical analyzer. The results showed dietary intake of Zn and Cu above the reference values with no differences observed between the two groups (p>0.05). Plasma and erythrocyte normocupremia as well as alteration in the Zn pool, with its reduced plasma concentrations and high in the erythrocytes, were observed in both groups (p>0.05). The plasma Cu/Zn ratio were not significantly different in patients with and without AD (p>0.05). The eSOD activity was high in both patient groups (p>0.05). However, among elderly patients with AD there was a positive correlation between this marker and dementia severity. According to our study results, we conclude that plasma and erythrocyte concentrations of Cu and Zn, as well as Cu/Zn ratio among elderly individuals is not related to Alzheimer's Disease. However, antioxidant activity of eSOD is associated with dementia severity.

Volatile compounds and palynological analysis from pollen pots of stingless bees from the mid-north region of Brazil

ABSTRACT Samburá is the botanical pollen nectar agglutinated by salivary secretions of bees. Stingless bee pollen samples were collected in three periods of the year in Monsenhor Gil town, PI, Brazil, for extraction of volatile constituents by different techniques, analyzed by gas chromatography-mass spectrometry (GC-MS) and the palynological analysis used to identify the dominant pollen. Among the volatile compounds identified, kaur-16-ene, methyl and ethyl hexadecanoate, methyl linoleate and heneicosane were identified more frequently in the studied parameters: period of sample collection and extraction techniques used. The palynological analysis identified the pollen of Mimosa caesalpiniifolia Benth. as the dominant pollen in all samples studied.

Retrospective study of dental trauma in children with autism spectrum disorders: a paired study.

The objective was to evaluate the history of traumatic dental injury (TDI) among children with and without autism spectrum disorders (ASD) at the Centro Integrado de Educação Especial (CIES), in Teresina, Brazil. The dental records of 228 children, 114 with ASD (SG = study group) and 114 without ASD (CG = control group), paired by age, gender and socioeconomic characteristics between January 2007 and September 2014 were reviewed. Data were analyzed using chi-square test and multivariate logistic regression (alpha = 5.0%). Dental trauma in SG was lower than in the CG (24.6% and 41.2%, respectively, p = 0.007). The risk of trauma was lower among males in SG (OR: 0.35; 95%CI: 0.18 to 0.67). The likelihood of TDI in SG was 3.17 higher in females than that of males (p = 0.040). The prevalence of TDI was lower in ASD individuals compared to controls. Dental trauma was higher among ASD girls than ASD boys.

Survival time of direct dental restorations in adults / Sobrevida de restaurações dentárias diretas em adultos

Introduction: The presence of dental caries is the main reason for the placement and replacement of restorations. Maintaining restorations to a satisfactory clinical condition is a challenge, despite the evolution of materials and surgical operative techniques. Objective: To investigate the survival time and technical-operatory characteristics of dental restorations among adults in Teresina-PI. Material and method: Data collection was carried out from September 2009 to January 2010 at a non-profit dental service. Data were collected at the moment of restoration replacement. The sample consisted of 262 defective restorations in 139 individuals. Survival time was calculated using the placement date that was registered on the individual’s dental form. Kruskal-Wallis and Mann-Whitney tests were used to compare the survival time of the different types of restorations and the chi-square test was used to assess the association between qualitative variables, at a 5% significance level. Result: The median survival time of the restorations was 2 years. The survival time for amalgam was higher than for composite and glass ionomer cement (p=0.004). The most replaced dental material was the composite (66.4%). The majority of the replaced restorations had been placed in anterior teeth, in proximal surfaces. Conclusion: Amalgam restorations have a longer survival time than composite resin. Technical and operatory variables had no influence on the survival time of restorations. Dental restorations have a low survival time and this fact might be associated with the decion-making process that is adopted by the professionals.

Introdução: A cárie dentária é o principal motivo para a instalação e troca de restaurações. A preservação destas em condição clínica satisfatória é um desafio, apesar da evolução dos materiais e técnicas cirúrgico-operatórias. Objetivo: Investigar o tempo de sobrevida e características técnico-operatórias das restaurações dentárias diretas de adultos em Teresina, Piauí. Material e método: A coleta de dados ocorreu de setembro de 2009 a janeiro de 2010, em clínicas de tratamento odontológico sem fins lucrativos. Os dados técnicos e operatórios do preparo cavitário e da restauração foram coletados no momento da substituição. A sobrevida foi calculada a partir da data de instalação que constava no prontuário. Os dados foram registrados em um formulário criado com esse fim. Kruskal-Wallis e Mann-Whitney foram empregados para comparar a sobrevida dos diferentes tipos de restaurações e o teste qui-quadrado para associações entre variáveis qualitativas, ambos com nível de significância de 5%. Resultado: As 262 substituições de restaurações deficientes estavam em 139 pacientes. A mediana de sobrevida das restaurações foi 2 anos. As restaurações de amálgama tiveram sobrevivência maior que as de resina composta (p=0,004). O material restaurador mais substituído foi resina composta (66,4%). A maioria das restaurações localizava-se em dentes anteriores e em preparos proximais. Conclusão: As restaurações de amálgama teve sobrevida maior que as de resina composta. As variáveis técnico-operacionais não influenciaram na taxa de substituições. As restaurações diretas possuem reduzido tempo de sobrevida o que pode estar associada à filosofia adotada pelo serviço para o tratamento fornecido.

Rio Grande do Norte, Brazil, voluntary bone marrow donors registry analysis.

OBJECTIVE: this study aimed to report the allele and haplotype frequencies of volunteer bone marrow donors (VBMD) from the state of Rio Grande do Norte (RN) who were enrolled in the Brazilian Volunteer Bone Marrow Donor Registry (REDOME). METHODS: the sample comprised 12,973 VBMD who had their allele and haplotype frequencies calculated by Arlequin 3.5.1.2. A multivariate analysis of the data was obtained through a principal component analysis (PCA) and hierarchical cluster analysis (HCA) performed with SPSS 8.0. RESULTS: the most frequent allelic group was HLA-A*02, followed by -DRB1*13, -DRB1*04, -DRB1*07, -B*44, -B*35, -A*24 and -DRB1*01. Of the 2,701 haplotypes observed, the three most frequent were HLA-A*01 B*08 DRB1*03 (1.62%), -A*29 B*44 DRB1*07 (1.56%) and -A*02 B*44 DRB1*04 (1.29%). These haplotypes were in linkage disequilibrium. RN allele and haplotype frequencies were very similar to those in other Brazilian states in which similar studies have been performed. The PCA revealed that RN is highly genetically similar to Caucasian populations, especially those from Iberian countries, which strongly influenced the state's ethnic composition. Africans and Amerindians also influenced the RN population structure, to a lesser extent. CONCLUSION: the HCA reinforced the conclusion that, despite its highly admixed profile, the RN population is genetically similar to European and European-descended populations. The PCA also showed that RN cities do not contribute to the same extent to REDOME, with less populous cities being underrepresented, indicating the need to enroll more VBMD from these smaller cities to faithfully depict the state's population structure in the database.

Farmacopeia natural de comunidades rurais no Estado do Piauí, Nordeste do Brasil / Natural Pharmacopeia of Rural Communities in the State of Piauí, Northeast of Brazil

Objetivou-se conhecer as plantas medicinais, as formas de usos e indicações terapêuticas atribuídas pelas comunidades Pau-Arrastado, Salinas e Resolvido. Utilizaram-se entrevista semiestruturada e turnês guiadas e seguiu-se metodologia botânica usual. Amostraram-se 93 pessoas (51,9% do total). As espécies foram agrupadas em 18 categorias de doenças, de acordo com a Organização Mundial de Saúde (OMS). Calculou-se o Fator de Consenso dos Informantes (FCI) e a Importância Relativa (IR). Referiram-se 81 espécies, em 40 famílias botânicas e 69 gêneros, sendo 75,3% nativas. A família mais destacada foi Fabaceae (18,5%), as folhas foram as partes mais usadas (32%) e o preparo mais adotado foi a tintura (38,2%). Destacaram-se os sistemas corporais: agentes de infecções bacterianas e virais (27,2%), doenças do aparelho digestivo (22,4%) e genitourinário (19,5%). Croton campestris A. St. Hil. e Ximenia americana L. foram as espécies mais versáteis, com IR (2,00). Houve maior consenso para as plantas indicadas no tratamento de doenças do fígado. (AU)

The purpose of this work is to know more about medicinal plants, forms of usage and therapeutic indications determined by the communities of Pau-Arrastado, Salinas and Resolvido. We used semi-structured interviews, guided tours and followed the usual botanical methodology. The study sample included 93 individuals (51.9% of the total). Species were grouped into 18 categories of disease, according to the World Health Organization (WHO). We calculated the Factor of Informant Consensus (FIC) and the Index of Relative Importance (IRI). They included eighty-one (81) species, belonging to 40 botanical families and 69 genera were referred, of which 75.3% were native ones. The most prominent family was Fabaceae (18.5%), and the leaves were the most used parts (32%). The preparation method most used was dye (38.2%). The highlights were the body systems: agents of bacterial and viral infections (27.2%), digestive system diseases (22.4%) and genitourinary diseases (19.5%). Croton campestris A. St. Hil. and Ximenia americana L. were the most versatile with an IRI of 2.00. There was a greater consensus for the plants indicated for the treatment of liver diseases.(AU)

Dentin hypersensitivity treatment of non-carious cervical lesions - a single-blind, split-mouth study.

This study aims to compare the in vivo effect of a desensitizing therapy associated with a restorative technique for the treatment of cervical dentin hypersensitivity (CDH) in non-carious lesions. The sample consisted of 68 teeth with moderate or severe dentin hypersensitivity in 17 individuals (one tooth per quadrant). The sensitivity levels of the teeth were scored, and the teeth were randomly distributed into four groups: T1 - desensitizing gel applied once per week until remission of pain; T2 - desensitizing gel applied once per week followed immediately by restoration with resin composite (Filtek Z250, 3M Espe); T3 - desensitizing gel once per week until remission of pain and then restoration with resin composite; and T4 - restoration with resin composite. Dentin hypersensitivity was assessed at 0, 7, 30, 90 and 180 days. The Kruskal-Wallis, Wilcoxon and Mann-Whitney (p < 0.05) tests were used to compare the treatments. The mean baseline CDH scores were T1 - 2.41, T2 - 2.41, T3 - 2.47, and T4 - 2.70 (p > 0.05). At seven and 180 days, the mean CDH scores were as follows: T1 - 1.47/0.65, T2 - 1.35/0.71, T3 - 0.71/0.53, and T4 - 1.12/0.59, all of which were significantly lower (p < 0.001) than the baseline scores. The scores at 30, 90 and 180 days were not significantly different when compared to the score of the previous period. At 180 days, CDH scores were similar among groups (p > 0.05). Teeth with moderate or severe hypersensitivity that required a filling responded similarly regardless of whether the desensitizing procedure was carried out prior to the filling.

The impact of the cost of oral hygiene products on the domestic budget in the urban region of a midsize Brazilian capital city / O impacto do custo de produtos de higiene bucal sobre o orçamento doméstico na zona urbana de uma capital de porte médio Brasileira

OBJECTIVE: To evaluate the impact of the cost of oral hygiene products in Teresina, Piauí, on the Brazilian minimum salary (MS) over the period of two years. METHODS: The writer of this study visited 12 businesses from five geographical areas of the city during four consecutive months in 2011 and 2013 to collect the prices of toothbrushes, toothpaste, dental floss and mouth rinse solutions of different brands. The prices were used to calculate the monthly expense that one individual would have if they consumed the ideal quantity of the products, as recommended by the dental literature. Brazil's MS at the time of the study was used as a parameter to calculate the impact of the cost of the items on the family budget. RESULTS: The mean monthly cost per individual was R$ 17.93 in 2011 (2.88% of the MS) and R$ 24.92 in 2013 (3.67% of the MS). There was an increase of 38.9 % in the mean price of products and the impact on the MS increased by 27.43 % during the study period. CONCLUSION: The impact of the cost of the oral care items was high on the Brazilian MS for the studied region. Dentists should be aware that the cost of these products can be an obstacle for their patients. .

OBJETIVO: Avaliar o impacto do custo dos produtos de higiene oral em Teresina, Piaúi sobre a o salário mínimo brasileiro ao longo de dois anos de observação. MÉTODOS: Doze estabelecimentos comerciais nas zonas geográficas do município foram visitados em quarto meses consecutivos em 2011 e 2013 para coletar o preço de escovas dentais, dentifrícios, fios dentais e antissépticos bucais de diferentes marcas. Para o cálculo do consumo mensal, considerou-se que os produtos foram consumidos em quantidade ideal para o uso. Para o impacto do custo dos itens, o salário mínimo brasileiro na época do estudo foi usado como parâmetro. RESULTADOS: O custo mensal médio por indivíduo seria de R$17,93 em 2011 (2,88% do salário mínimo) e R$24,92 em 2013 (3,67% do salário mínimo). CONCLUSÃO: Houve aumento de 38,9% no preço dos produtos e o impacto sobre o SM aumentou em 27,43% no período do estudo. Os cirurgiões-dentistas devem estar bem informados sobre o custo desses produtos ao prescrevê-los a seus pacientes. .

Rio Grande do Norte, Brazil, voluntary bone marrow donors registry analysis / Análise do registro de doadores voluntários de medula óssea do Rio Grande do Norte, Brasil.

Objective: this study aimed to report the allele and haplotype frequencies of volunteer bone marrow donors (VBMD) from the state of Rio Grande do Norte (RN) who were enrolled in the Brazilian Volunteer Bone Marrow Donor Registry (REDOME). Methods: the sample comprised 12,973 VBMD who had their allele and haplotype frequencies calculated by Arlequin 3.5.1.2. A multivariate analysis of the data was obtained through a principal component analysis (PCA) and hierarchical cluster analysis (HCA) performed with SPSS 8.0. Results: the most frequent allelic group was HLA-A*02, followed by -DRB1*13, -DRB1*04, -DRB1*07, -B*44, -B*35, -A*24 and -DRB1*01. Of the 2,701 haplotypes observed, the three most frequent were HLA-A*01 B*08 DRB1*03 (1.62%), -A*29 B*44 DRB1*07 (1.56%) and -A*02 B*44 DRB1*04 (1.29%). These haplotypes were in linkage disequilibrium. RN allele and haplotype frequencies were very similar to those in other Brazilian states in which similar studies have been performed. The PCA revealed that RN is highly genetically similar to Caucasian populations, especially those from Iberian countries, which strongly influenced the state’s ethnic composition. Africans and Amerindians also influenced the RN population structure, to a lesser extent. Conclusion: the HCA reinforced the conclusion that, despite its highly admixed profile, the RN population is genetically similar to European and European-descended populations. The PCA also showed that RN cities do not contribute to the same extent to REDOME, with less populous cities being underrepresented, indicating the need to enroll more VBMD from these smaller cities to faithfully depict the state’s population structure in the database. .

Objetivo: relatar as frequências alélicas e haplotípicas do HLA-A, -B e -DRB1 de doadores voluntários de medula óssea (DVMO) do Rio Grande do Norte (RN), inscritos no Registro Nacional de Doadores de Medula Óssea (REDOME). Metodologia: 12.973 DVMO tiveram suas frequências alélica e haplotípica calculadas pelo programa Arlequin 3.5.1.2. Uma análise multivariada dos dados foi obtida por meio da Análise de Componente Principal (ACP) e da Análise de Cluster Hierárquico (ACH) realizadas pelo SPSS 8.0. Resultados: os grupos alélicos mais frequentes foram HLA-A*02, seguido por -DRB1*13, -DRB1*04, -DRB1*07, -B*44, -B*35, -A*24 e -DRB1*01. Dos 2.701 haplótipos observados, os três mais frequentes foram HLA-A*01 B*08 DRB1*03 (1,62%), -A*29 B*44 DRB1*07 (1,56%) e -A*02 B*44 DRB1*04 (1,29%), que se encontravam em desequilíbrio de ligação. As frequências alélicas e haplotípicas do RN são bastante similares às de outros estados brasileiros em que trabalhos semelhantes foram executados. A ACP revelou ser o RN geneticamente muito semelhante a populações caucasianas, especialmente a dos países ibéricos, os quais influenciaram fortemente na composição étnica do Estado. Africanos e ameríndios também contribuíram para a estrutura populacional, mas em menor proporção. Conclusão: a ACH reforçou a conclusão de que, apesar de seu perfil miscigenado, a população do RN se assemelha geneticamente com populações europeias e que descendem das europeias. A ACP também mostrou que as cidades do RN não contribuem equitativamente na composição do REDOME, de modo que cidades pouco populosas estão sub-representadas, apontando a necessidade de cadastrar mais DVMO dessas cidades para que a estrutura da população seja fielmente retratada. .

Cephalometric and anthropometric data of obstructive apnea in different age groups / Medidas cefalométricas e antropométricas do índice de apneia e hipopneia em diferentes faixas etárias

Introduction: Patients with obstructive sleep apnea syndrome usually present with changes in upper airway morphology and/or body fat distribution, which may occur throughout life and increase the severity of obstructive sleep apnea syndrome with age. Objective: To correlate cephalometric and anthropometric measures with obstructive sleep apnea syndrome severity in different age groups. Methods: A retrospective study of cephalometric and anthropometric measures of 102 patients with obstructive sleep apnea syndrome was analyzed. Patients were divided into three age groups (≥20 and <40 years, ≥40 and <60 years, and ≥60 years). Pearson's correlation was performed for these measures with the apnea-hypopnea index in the full sample, and subsequently by age group. Results: The cephalometric measures MP-H (distance between the mandibular plane and the hyoid bone) and PNS-P (distance between the posterior nasal spine and the tip of the soft palate) and the neck and waist circumferences showed a statistically significant correlation with apnea-hypopnea index in both the full sample and in the ≥40 and <60 years age group. These variables did not show any significant correlation with the other two age groups (<40 and ≥60 years). Conclusion: Cephalometric measurements MP-H and PNS-P and cervical and waist circumfer- ences correlated with obstructive sleep apnea syndrome severity in patients in the ≥40 and <60 age group. .

Introdução: Pacientes com a síndrome da apneia obstrutiva do sono (SAOS) geralmente apresentam alterações na morfologia das vias aéreas superiores e/ou na distribuição da gordura corporal, que podem ocorrer durante a vida e aumentar a gravidade da SAOS com a idade. Objetivo: Correlacionar medidas cefalométricas e antropométricas com a gravidade da SAOS em diferentes faixas etárias. Método: Estudo retrospectivo de medidas cefalométricas e antropométricas de 102 pacientes portadores de SAOS. Os pacientes foram divididos em três faixas etárias (≥20 e <40 anos, ≥40 e <60 anos, e ≥60 anos). Foi realizada correlação de Pearson destas medidas com o índice de apneia-hipopneia (IAH) na amostra completa e depois por faixa etária. Resultados: As medidas cefalométricas MP-H (distância entre o plano mandibular e o osso hioide) e PNS-P (distância entre a espinha nasal posterior e a ponta do palato mole) e as circunferências cervical e abdominal apresentaram correlação estatisticamente significante com o IAH tanto na amostra total quanto na faixa de <40 e ≥ 60 anos. Estas variáveis não mostraram correlação significante com as outras duas faixas etárias (≤ 40 e ≥ 60 anos). Conclusão: As medidas cefalométricas MP-H e PNS-P e as circunferências cervical e abdominal apresentaram correlação com a gravidade da SAOS em pacientes na faixa etária de ≥40 e <60 anos. .