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Urologe A ; 52(4): 576-9, 2013 Apr.
Article in German | MEDLINE | ID: mdl-23571802

ABSTRACT

The PREFERE study is a multicenter randomized study of patients with low or early intermediate risk for prostatic cancer. The four treatment options, radical prostatectomy, percutaneous irradiation therapy, permanent seed implantation and active surveillance recommended by the German S3 guidelines and international guidelines will be tested and compared with respect to effectiveness and potential side effects. Over a period of 4 years a total of 7,600 patients are to be recruited and assigned to 1 of these 4 therapy forms according to personal preference (by possible exclusion of 1 or 2 therapy options) in a 2-4 arm study design by randomization.


Subject(s)
Brachytherapy/statistics & numerical data , Prostatectomy/statistics & numerical data , Prostatic Neoplasms/epidemiology , Prostatic Neoplasms/therapy , Radiotherapy, Conformal/statistics & numerical data , Germany/epidemiology , Humans , Male , Prevalence , Prostatic Neoplasms/diagnosis , Treatment Outcome
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