ABSTRACT
In general, hosts develop resistance to ticks after repeated infestations; nevertheless, several studies on naturally occurring host-tick interactions were unable to detect resistance of hosts to ticks even after repeated infestations. The purpose of this investigation was to study the type of cutaneous hypersensitivity to unfed nymphal extract of A. cajennense in dogs, which, unlike guinea pigs, do not develop resistance. A first, but no second, peak in skin reaction was observed, suggesting that cellular immunity is an important mechanism of resistance to ticks. This may partially explain why guinea pigs, but not dogs, develop resistance against ticks.
Subject(s)
Dog Diseases/immunology , Hypersensitivity, Delayed/veterinary , Ixodidae/immunology , Tick Infestations/veterinary , Animals , Arachnid Vectors/immunology , Dog Diseases/parasitology , Dogs , Guinea Pigs , Host-Parasite Interactions , Hypersensitivity, Delayed/immunology , Hypersensitivity, Delayed/parasitology , Immunity, Cellular , Immunity, Innate , Ixodidae/physiology , Species Specificity , Tick Infestations/immunologyABSTRACT
Ticks have long been regarded as constraints to humans and domestic animals, but hosts often develop resistance to ticks after repeated infestations. The purpose of this investigation was to study the possible acquisition of immunity in domestic dogs to nymphs of A. cajennense by determining the tick alimentary performance after successive controlled infestations. Mean engorged weight of nymphs was not significantly different among the three infestations; molting rate from nymph to adult ticks, and the percentage of nymph recovery were also very close in all infestations. These results are similar to those obtained in studies of the dog-adult Rhipicephalus sanguineus interface. It is concluded that domestic dogs do not develop resistance against nymphs of A. cajennense ticks.
