1.
Org Biomol Chem
; 15(36): 7572-7579, 2017 Sep 20.
Article
in English
| MEDLINE
| ID: mdl-28858370
ABSTRACT
Conformational mobility is a core property of organic compounds, and conformational analysis has become a pervasive tool for synthetic design. In this work, we present experimental and computational (employing Density Functional Theory) evidence for unusual intramolecular hydrogen bonding interactions in a series of α-acylmethane derivatives, as well as a discussion of the consequences thereof for their NMR spectroscopic properties.