[Doppler echocardiography analysis of left ventricular inflow patterns in hypertrophic obstructive cardiomyopathy pre- and postoperatively]. / Dopplerechokardiographische Analyse des linksventrikulären Einflussverhaltens bei hypertrophischer obstruktiver Kardiomyopathie prä- und postoperativ.

The aim of the present study was to assess abnormalities of left ventricular filling by Doppler echocardiography in patients with hypertrophic obstructive cardiomyopathy and to investigate whether a myectomy, in addition to normalizing flow, also improves diastolic function. In part A of the study, 40 patients with diagnosed invasive HOCM (29 patients with a gradient at rest, 11 patients with a gradient only after provocation) were compared with 20 normal subjects. The blood flow in the left ventricular inflow tract was examined by means of Doppler echocardiography. At the same time the isovolumic relaxation (IVR) period and the mitral valve opening area (MVOA) were determined using M-mode and the two-dimensional echocardiography, respectively. In part B of the study, 17 patients were examined directly preoperatively and again postoperatively (mean 14 days). Nine patients were then examined at a later date (mean 8.6 months).(ABSTRACT TRUNCATED AT 250 WORDS)