ABSTRACT
The Research to Practice Column is designed to improve translational research critique skills of nurse practitioners (NPs). In this issue, the article "Randomized study of IV prochlorperazine plus diphenhydramine vs IV hydromorphone for migraine" is discussed in the context of a patient with an acute headache presenting to the emergency department (ED). The study was designed to assess the efficacy of intravenous prochlorperazine and diphenhydramine as compared with intravenous hydromorphone for patients with acute migraine in the ED. With the growing trend to avoid the use of opiates to curb potential addiction and increased ED length of stay, NPs need to be aware of efficacious, evidence-based treatments for acute migraines, a common ED presentation.
Subject(s)
Analgesics, Opioid/therapeutic use , Diphenhydramine/therapeutic use , Dopamine Antagonists/therapeutic use , Hydromorphone/therapeutic use , Hypnotics and Sedatives/therapeutic use , Migraine Disorders/drug therapy , Prochlorperazine/therapeutic use , Acute Disease , Administration, Intravenous , Adult , Analgesics, Opioid/administration & dosage , Diphenhydramine/administration & dosage , Dopamine Antagonists/administration & dosage , Double-Blind Method , Drug Therapy, Combination , Emergency Service, Hospital , Female , Humans , Hydromorphone/administration & dosage , Hypnotics and Sedatives/administration & dosage , Male , Pain Measurement , Prochlorperazine/administration & dosage , Randomized Controlled Trials as Topic , Treatment OutcomeABSTRACT
The Research to Practice Column is designed to improve translational research critique skills of advanced practice nurses. In this issue, the article "Risk of Acute Kidney Injury After Intravenous Contrast Media Administration" () is discussed in the context of a patient presenting to the emergency department with acute abdominal pain. The study was designed to assess the risk of acute kidney injury and adverse clinical outcomes in patients receiving intravenous contrast for computed tomography. Advanced practice nurses need to be aware of advances in types of intravenous contrast and current recommendations for administration of intravenous contrast for diagnostic purposes in patients at risk for acute kidney injury to facilitate making timely and accurate diagnoses.
