1.
Org Lett
; 6(23): 4343-5, 2004 Nov 11.
Article
in English
| MEDLINE
| ID: mdl-15524479
ABSTRACT
1,5-Cyclooctadiene can be stereoselectively transformed into a substituted bicyclo[3.3.0]octane ring system under palladium catalysis with concomitant formation of three carbon-carbon bonds. Reaction with an aryl iodide or triflate and malonate gives an exo-endo product, while the reaction with a malonate in the presence of oxygen affords a bis-endo adduct.