ABSTRACT
Paragangliomas can exist anywhere in the distribution of neural crest derived cells. In the spermatic cord, they are exceedingly rare. We report a case of histologically discovery, occurring in a man of 50 years who had a para-testicular mass, painless, firm without other signs associated. In view of this observation and a review of the literature, we propose to establish the epidemiological profile and study the prognostic and the clinicopathologic features of this tumor.
Subject(s)
Genital Neoplasms, Male/pathology , Paraganglioma/pathology , Spermatic Cord , Humans , Male , Middle AgedABSTRACT
PURPOSE: Also called acute febrile neutrophilic dermatosis, Sweet's syndrome is an inflammatory disorder with a prominent cutaneous expression. It is characterized by a variety of manifestations, clinical and histological findings. The objective of this study was to describe their clinical, pathological and therapeutic characteristics. METHODS: We report on a series of 47 patients who presented a Sweet's syndrome, collected in our institution in Tunis between 1997 and 2011. RESULTS: The patient population consisted of 11 men and 36 women. The mean age was 47 years with extreme ranging from 28 to 74 years. An associated disorder was observed in ten patients: inflammatory disease (three cases), inflammatory bowel disease (two cases), tuberculosis (three cases) and diabetes (three cases). One case of pregnancy was observed. Cutaneous lesions consisted of erythematous plaques or nodules. Lesions were located mainly on the upper or lower extremities. All biopsy specimens demonstrated a dermal infiltrate composed predominantly of neutrophils. Fibrinoid necrosis and intramural inflammation were observed in eight cases. CONCLUSION: The skin disorder can precede, follow, or appear concurrent with the diagnosis of an associated disease which requires careful surveillance.
Subject(s)
Sweet Syndrome/pathology , Adult , Aged , Anti-Infective Agents/therapeutic use , Autoimmune Diseases/complications , Crohn Disease/complications , Diabetes Complications , Female , Glucocorticoids/therapeutic use , Gout Suppressants/therapeutic use , Histamine Antagonists/therapeutic use , Humans , Male , Middle Aged , Pregnancy , Pregnancy Complications , Retrospective Studies , Sweet Syndrome/complications , Sweet Syndrome/drug therapy , Tuberculosis/complicationsSubject(s)
Astrocytoma/pathology , Brain Neoplasms/pathology , Neoplasm Recurrence, Local , Astrocytoma/radiotherapy , Astrocytoma/surgery , Brain Neoplasms/radiotherapy , Brain Neoplasms/surgery , Child, Preschool , Diagnosis, Differential , Humans , Male , Neoplasm Invasiveness , Neoplasm Recurrence, Local/pathology , Prognosis , Radiotherapy, Adjuvant , Treatment Failure , Treatment OutcomeABSTRACT
Cryptococcus neoformans is a ubiquitous yeast that causes opportunistic infections mainly involving the central nervous system. Cryptococcoma is a rare entity characterized by a solid, tumor-like mass that is usually located in the cerebral hemispheres or cerebellum. Spinal involvement is rare with only 6 cases reported in literature. Bony involvement is also a rare occurrence that has been observed in only 5 to 10% of reported cases of infection by Cryptococcus neofomans. The purpose of this report is to describe a case of paraplegia due to cryptococcal spondylitis with spinal cord involvement in an HIV-seronegative patient with a history of systemic sarcoidosis. Diagnosis was achieved by histological examination of the surgical specimen.
