1.
Chem Commun (Camb)
; 47(40): 11309-11, 2011 Oct 28.
Article
in English
| MEDLINE
| ID: mdl-21922105
ABSTRACT
A series of forcible curved circular DNAs (cDNAs) were prepared to investigate the recognition features of human Topoisomerase I (hTopo I). The IC(50) can be modulated by the curvature degrees of cDNA. In addition, preferential bindings of hTopo I to cDNA with high curvature have been observed by AFM and EMSA.
