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PLoS One ; 15(10): e0240602, 2020.
Article in English | MEDLINE | ID: mdl-33119646

ABSTRACT

BACKGROUND: Diabetic polyneuropathy is associated with significant physical disability among older adults. However, their frequency and correlates are not well known in the older adults in Sub-Saharan-Africa. The objectives were to evaluate the hospital-based prevalence of diabetic polyneuropathy and identify its correlates in older adults. METHODS: Over a period of 5 months, a cross-sectional survey was carried out at Douala Laquintinie Hospital (DLH), a main reference hospital in Douala, the economic capital of Cameroon. Participants in our study group comprised all patients with type 2 diabetes, whatever the reason for their reporting to the hospital. Diabetic Polyneuropathy was defined according to a Diabetic Neuropathy Examination score > 3/16. RESULTS: A total of 159 older adults with diabetes were examined during this recruitment period, among whom 106 (66.7%) were women. The mean age was 68.3 ± 6.5 years. Diabetes median duration was 108 months. For all patients assessed using the Diabetic Neuropathy Examination score, polyneuropathy was reported in 31.4%; among them, polyneuropathy proved symptomatic in 78% of them. Correlates of polyneuropathy were glycated hemoglobin (p = 0.049), HIV infection (p = 0.031) and albuminuria (p< 0.001), even after adjustment for age, gender and duration of diabetes. CONCLUSION: A third of older adults with diabetes who visited our hospital were diagnosed with prevalent diabetes-related polyneuropathy. It shows that early detection is required through routine screening and regular follow-up examinations in order to reduce the risk of disability and improve the quality of life in elderly diabetics.


Subject(s)
Diabetes Mellitus, Type 2/epidemiology , Diabetic Neuropathies/epidemiology , HIV Infections/epidemiology , Neuralgia/epidemiology , Africa South of the Sahara/epidemiology , Aged , Cameroon/epidemiology , Diabetes Mellitus, Type 2/blood , Diabetes Mellitus, Type 2/complications , Diabetes Mellitus, Type 2/pathology , Diabetic Neuropathies/blood , Diabetic Neuropathies/complications , Diabetic Neuropathies/pathology , Female , Geriatric Assessment , Glycated Hemoglobin/metabolism , HIV Infections/blood , HIV Infections/complications , HIV Infections/pathology , Humans , Male , Middle Aged , Neuralgia/blood , Neuralgia/pathology , Quality of Life , Risk Factors
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