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Bioorg Med Chem Lett
; 16(13): 3430-3, 2006 Jul 01.
Article
in English
| MEDLINE
| ID: mdl-16632349
ABSTRACT
The synthesis and preliminary structure-activity relationship of a series of pyrrolidinones are described. These pyrrolidinones have been characterized as novel non-nucleoside reverse transcriptase inhibitors (NNRTIs) which are highly potent against wild-type and drug-resistant human immunodeficiency viruses (HIV-1).