Heavy metal exposure risk associated with ingestion of Oreochromis niloticus and Coptodon kottae harvested from a lacustrine ecosystem.

Lacustrine ecosystems have not been widely assessed for heavy metal contamination and associated health risks; yet, they could be accumulating these contaminants to the detriment of aquatic organisms and communities relying on them for various aspects. The water quality index (WQI) and concentrations of heavy metals including As, Cd, Co, Cu, Cr, Fe, Mn, Ni, Pb, and Zn in water, sediment, Oreochromis niloticus, and in the endemic and endangered Coptodon kottae in Lake Barombi Kotto in Cameroon were determined to evaluate fish heavy metal bioaccumulation, and heavy metal exposure risk posed to communities consuming these fish species. The WQI of the lake was found to be excellent with heavy metal concentrations that were lower than what was obtained in the sediments and fish samples. Mean heavy metal concentrations in sediment ranged from 0.86 ± 0.03 mg/kg for Cd to 560.1 ± 11.15 mg/kg for Fe. In both fish species, Fe, Mn, and Cu had the highest concentrations. Though the heavy metal concentrations in the lake water were low, heavy metal bioconcentration factors for both fish species were very high ranging from 1.6 for Fe to 1568 for Mn. The concentration patterns of heavy metals in the organs of both fish species followed the order bones > gut > muscle. Consumption of these two fish species contributes less than 1.0% of the permissible tolerable daily intake (PTDI) and provisional tolerable weekly intake (PTWI) of these metals with lead (Pb) having the potential to exceed permissible exposure levels when high amounts of these fish are consumed by adults.

Ligninolytic enzyme activity and removal efficiency of pharmaceuticals in a water matrix by fungus Rhizopus sp. Isolated from cassava.

Residual amounts of pharmaceutical compounds (PhCs) and by-products are continually released into surface water with effluents from conventional wastewater treatment plants (WWTPs). This study evaluated the ability of fungal isolate to remove selected PhCs [carbamazepine (CBZ), diclofenac (DCF) and ibuprofen (IBP)] from wastewater. The fungus used was Rhizopus sp. which was isolated from tuberous roots of cassava (Manihot esculenta). The isolate exhibited an important removal efficiency up to 100% and this was linked to ligninolytic enzymatic activity for lignin peroxidase (15.29 ± 2.69U/L) and manganese peroxidase (85.22 ± 4.26U/L), except laccase. This activity was optimum on day 9 of treatment. PhC metabolites were identified during the experiment revealing the existence of a biotransformation process catalysed by the isolated fungus. The disappearance of PhCs was attributed to their biosorption and biotransformation. However, it was not possible to establish a relationship between the ligninolytic enzymatic activity and the removal efficiency, which leads to the conclusion that there are other fungal metabolites which also play an important role in the biotransformation and biodegradation of the selected PhCs.

Evaluation of indoor and outdoor air quality in university academic buildings and associated health risk.

Air pollution is associated with several detrimental health conditions. This study assessed comfort parameters, priority air pollutants, hydrogen sulphide (H2S), non-methane hydrocarbons (NMHCs), and volatile organic compounds (VOCs) in natural science departments in a university to understand their role in air pollutant concentrations in university environments and associated health risks. Levels of air pollutants in the departments varied. High CO2 concentrations existed in all departments with highest levels of NMHC and VOC observed in the biochemistry, microbiology and biotechnology (BMBT) department. Highest Air quality index value of 111.3 was recorded for NO2 in the BMBT department. Health risk associated with exposure to these pollutants was highest for occupants in the physiology, followed by the biodiversity, and finally BMBT department. Natural science departments seem to contribute significant amounts of H2S, NO2, NMHCs and TVOCs in university campuses. Additional ventilation and frequent monitoring of air quality in these departments are recommended.

Endocrine-disruptive chemicals as contaminants of emerging concern in wastewater and surface water: A review.

Population growth followed by rapid development of industrialisation has caused serious environmental pollution with contaminants of emerging concern found in wastewater and surface water. As one of the most important resources for human survival, water is daily polluted by endocrine-disruptive chemicals (EDCs) including pharmaceuticals and personal care products, organic pollutants and heavy metals. Even at low concentrations in water bodies, chronic exposure to EDCs can cause adverse effects on human and environment health. The main concern with EDCs is the diseases they can generate in humans or wildlife by affecting the function of hormones in the body. Problems in the reproductive system, thyroid problems, Alzheimer's, cancer and obesity are some of the major effects of EDCs in humans. In wildlife, the reproductive system may be affected, including its levels of hatchability and vitellogenin. The efforts of the present review are on emphasising on the environmental concern on the occurrence and risk assessment of EDCs, their harmful effects in the ecosystem, human life, and wildlife, as a result of their incomplete removal from wastewater treatment plants. The review focuses on studies conducted in South Africa highlights the use of fungal bioreactors as a low-cost and eco-effective environmentally friendly wastewater treatment processes.

An analysis of human exposure to trace elements from deliberate soil ingestion and associated health risks.

Fifty-seven samples of soils commonly ingested in South Africa, Swaziland, Democratic Republic of Congo (DRC), and Togo were analyzed for the concentrations of arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), lead (Pb), manganese (Mn), nickel (Ni), and zinc (Zn) and their bioaccessibility in the human gastrointestinal tract. Bioaccessibility values were used to calculate daily intake, and hazard quotient of each trace element, and chronic hazard index (CHI) of each sample. Carcinogenic risk associated with As and Ni exposure were also calculated. Mean pseudo-total concentrations of trace elements in all samples were 7.2, 83.3, 77.1, 15.4, 28.6, 24.9, 56.1, 2.8, and 26.5 mg/kg for As, Cr, Mn, Co, Ni, Cu, Zn, Cd, and Pb, respectively. Percent bioaccessibility of Pb (13-49%) and Zn (38-56%) were highest among trace elements studied. Average daily intake values were lower than their respective reference doses for ell elements except for Pb in selected samples. Samples from DRC presented the highest health risks associated with trace element exposure with most of the samples having CHI values between 0.5 and 1.0. Some samples had higher than unacceptable values of carcinogenic risk associated with As and Ni exposure. Results indicate low trace element exposure risk from ingesting most of the soil samples.

Heavy metals in soils along unpaved roads in south west Cameroon: Contamination levels and health risks.

Soils enriched with heavy metals from vehicular emission present a significant exposure route of heavy metals to individuals using unpaved roads. This study assessed the extent of Cd, Cr, Co, Cu, Ni, Pb and Zn contamination of soils along unpaved roads in Cameroon, and the health risks presented by incidental ingestion and dermal contact with the soils using metal contamination factor (CF) pollution load index, hazard quotients (HQ) and chronic hazard index (CHI). CF values obtained (0.9-12.2) indicate moderate to high contamination levels. HQ values for Cr, Cd and Pb exceeded the reference doses. Moderate health hazard exists for road users in the areas with intense anthropogenic activities and high average daily traffic (ADT) volume according to CHI values (1-4) obtained. The economy and quality of life in cities with unpaved roads could be threatened by health challenges resulting from long-term exposure to heavy metal derived from high ADT volumes.

A Comparative Analyses of Granulometry, Mineral Composition and Major and Trace Element Concentrations in Soils Commonly Ingested by Humans.

This study compared the granulometric properties, mineralogical composition and concentrations of major and trace element oxides of commonly ingested soils (geophagic soil) collected from different countries with a view of understanding how varied they may be in these properties and to understand the possible health implications of ingesting them. Soil samples were collected from three different countries (South Africa, Swaziland and Democratic Republic of Congo (DRC)) and their granulometric properties, concentrations of major and trace element oxides as well as mineralogical composition determined. Differences were observed in the granulometric properties of geophagic soil from the three different countries with most of them having <20% clay content. The soils also showed varied degrees of weathering with values of Chemical Index of Alteration (CIA) and Chemical Index of Weathering (CIW) being between 60% and 99.9% respectively. The mineral assemblages of the soils from South Africa and Swaziland were dominated by the primary minerals quartz and feldspar whereas soils from DRC had more of kaolinite, a secondary mineral than primary minerals. Soils from DRC were associated with silt, clay, Al2O3, and CIA unlike most samples from South Africa which were associated with SiO2, sand, K2O, CaO, and MgO. The soils from Swaziland were closely associated with silt, H2O and Fe2O3(t). These associations reflect the mineralogy of the samples. These soils are not likely to serve as nutrient supplements because of the low concentrations of the nutrient elements contained. The coarse texture of the samples may also result in dental destruction during mastication. Sieving of the soils before ingestion to remove coarse particles is recommended to reduce the potential health threat associated with the ingestion of coarse-textured soils.