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Arch Pharm Res ; 33(2): 203-8, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20195819

ABSTRACT

Two new 2-C-beta-D-glucopyranosyl benzoic acid derivatives named mallonanosides A (1) and B (2) were isolated from the methanolic extract of the leaves of Mallotus nanus along with five known flavonoids, kaempferin (3), juglanin (4), quercitrin (5), myricitrin (6), and rhoifolin (7). Their structures were established on the basis of spectral and chemical evidence. Their antioxidant activities were shown to depend on the number of hydroxyl groups, and the location and species of sugar moiety.


Subject(s)
Antioxidants/isolation & purification , Antioxidants/pharmacology , Flavonoids/isolation & purification , Flavonoids/pharmacology , Free Radical Scavengers/isolation & purification , Free Radical Scavengers/pharmacology , Gallic Acid/analogs & derivatives , Glucosides/isolation & purification , Glucosides/pharmacology , Mallotus Plant , Vanillic Acid/analogs & derivatives , Antioxidants/chemistry , Flavonoids/chemistry , Free Radical Scavengers/chemistry , Gallic Acid/chemistry , Gallic Acid/isolation & purification , Gallic Acid/pharmacology , Glucosides/chemistry , Plant Extracts/pharmacology , Plant Leaves/chemistry , Reactive Oxygen Species/antagonists & inhibitors , Structure-Activity Relationship , Vanillic Acid/chemistry , Vanillic Acid/isolation & purification , Vanillic Acid/pharmacology
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