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1.
Hum Pathol ; 28(11): 1306-10, 1997 Nov.
Article in English | MEDLINE | ID: mdl-9385939

ABSTRACT

We present an unusual case of an aortic intimal sarcoma, which originally manifested itself by the presence of extensive radiologically osteolytic lesions in the long bones of the lower limbs. The histology of these was puzzling and was first considered to represent a low grade sarcoma of vasoformative tissue and subsequently skeletal angiomatosis. Despite a good initial clinical response to disodium etidronate, the patient ultimately developed small bowel infarction and the true diagnosis only came to light at autopsy. This revealed a tumour in the lower thoracic aorta which, unusually for aortic sarcoma, consisted of loosely packed bland spindle cells with no necrosis and infrequent mitoses. Immunocytochemistry was unhelpful but electron microscopy suggested myofibroblastic differentiation. The majority of previous reports of the tumour in the literature lack information on electron microscopy and immunocytochemistry and have suggested that these tumours are generally pleomorphic in appearance. Embolic phenomena and post mortem diagnosis are usual although occasional antemortem diagnosis has been made using computed tomography (CT) and magnetic resonance imaging (MRI) scanning with the latter being the investigation of choice.


Subject(s)
Aortic Diseases/pathology , Bone Neoplasms/secondary , Osteolysis, Essential/etiology , Sarcoma/secondary , Aorta, Thoracic/chemistry , Aorta, Thoracic/pathology , Biomarkers/analysis , Biopsy , Bone Neoplasms/diagnostic imaging , Fatal Outcome , Female , Humans , Immunohistochemistry , Intestinal Neoplasms/chemistry , Intestinal Neoplasms/secondary , Middle Aged , Radiography , Sarcoma/chemistry , Sarcoma/diagnostic imaging
2.
Injury ; 27(3): 209-11, 1996 Apr.
Article in English | MEDLINE | ID: mdl-8736299

ABSTRACT

Perilunate dislocation is a rare injury. The dorsal type, in which the distal row of the carpus displaces posterior to the lunate, is more common; the volar dislocation of the carpus on the lunate is an extremely rare injury. In addition to a case report of this rare injury, a probable mechanism is described with cadaveric studies. The proposed mechanism, to the author's best knowlege, has not been reported or recognized in the English literature, previously.


Subject(s)
Accidents, Traffic , Carpal Bones/injuries , Joint Dislocations/etiology , Motorcycles , Adult , Carpal Bones/diagnostic imaging , Humans , Joint Dislocations/diagnostic imaging , Ligaments, Articular/anatomy & histology , Male , Radiography
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