1.
Med Interne
; 14(1): 63-9, 1976.
Article
in English
| MEDLINE
| ID: mdl-946696
ABSTRACT
The case of two sisters is reported in whom morphological (multinucleated erythroblasts in the bone marrow) and serological (positive Ham test, negative sucrose and water-sugar tests) characteristics of a congenital dyserythropoietic anemia type II were found. Radioautographic, cytogenetic and electron microscope studies confirmed the presence of an inefficient erythropoiesis and of a membrane defect, common in this disease. The finding of a nil LAP score has never been reported so far.
Subject(s)
Anemia/genetics , Bone Marrow Cells , Bone Marrow/ultrastructure , Erythrocytes, Abnormal/ultrastructure , Erythropoiesis , Adolescent , Adult , Anemia/congenital , Anemia/pathology , Bone Marrow/pathology , Cell Membrane/ultrastructure , DNA/biosynthesis , Erythroblasts/ultrastructure , Female , Humans , Karyotyping
2.
Med Interna (Bucur)
; 23(5): 611-20, 1971 May.
Article
in Romanian
| MEDLINE
| ID: mdl-5284891
Subject(s)
Asparaginase/therapeutic use , Leukemia, Lymphoid/drug therapy , Adolescent , Adult , Female , Humans , Male , Middle Aged
3.
Med Interna (Bucur)
; 22(11): 1393-403, 1970 Nov.
Article
in Romanian
| MEDLINE
| ID: mdl-5533266
4.
Med Interna (Bucur)
; 21(9): 1037-49, 1969 Sep.
Article
in Romanian
| MEDLINE
| ID: mdl-5378236