ABSTRACT
The authors present a case in which the clinico-evolutive particularity was an association between a periventricular tumour (multiform glioblastoma) and acute renal failure. Considerations are made on clinical signs determined by the neoplastic process (apraxia-agnosia hyperthermia, etc.), and on the disseminated intravascular coagulation syndrome related to the acute renal failure.
Subject(s)
Acute Kidney Injury/diagnosis , Cerebral Ventricle Neoplasms/diagnosis , Glioblastoma/diagnosis , Kidney Cortex Necrosis/diagnosis , Acute Kidney Injury/pathology , Cerebral Ventricle Neoplasms/pathology , Cerebral Ventricles/pathology , Disseminated Intravascular Coagulation/diagnosis , Disseminated Intravascular Coagulation/pathology , Female , Glioblastoma/pathology , Humans , Kidney/pathology , Kidney Cortex Necrosis/pathology , Middle AgedSubject(s)
Acute Kidney Injury/therapy , Pregnancy Complications/therapy , Puerperal Disorders , Acute Kidney Injury/etiology , Acute Kidney Injury/mortality , Adult , Anti-Bacterial Agents/therapeutic use , Cesarean Section , Female , Furosemide/therapeutic use , Humans , Pregnancy , Pregnancy Complications/etiology , Pregnancy Complications/mortality , Renal DialysisSubject(s)
Anti-Infective Agents/adverse effects , Kidney/drug effects , Aminoglycosides/adverse effects , Aminoglycosides/metabolism , Anti-Bacterial Agents/adverse effects , Anti-Bacterial Agents/metabolism , Anti-Infective Agents/metabolism , Clinical Enzyme Tests , Dose-Response Relationship, Drug , Drug Hypersensitivity/immunology , Humans , Kidney/enzymology , Kidney/metabolism , Nephritis, Interstitial/chemically induced , Nephritis, Interstitial/immunology , Peptides/adverse effects , Peptides/metabolism , Rifampin/adverse effects , Rifampin/metabolismABSTRACT
Six observations are presented of patients receiving intermitent rifampicin treatment (900 mg twice weekly) that developed acute renal failure during treatment (4 cases) or when treatment was taken up again, after an interruption of 6 months (2 cases). Following anuria of 4--14 days and nitrogen retention between 248 and 521 mg, the evolution was favourable. Clinical, biological and immunological data (anti-rifampicin antibodies were detected in 1/8 and 1/16 in 3 cases) suggest the immune origin of this type of renal accidents.