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Nat Prod Res ; 34(13): 1874-1878, 2020 Jul.
Article in English | MEDLINE | ID: mdl-30689410

ABSTRACT

A new triterpenoid glucoside, leuctriterpencoside (1), along with two known compounds (2-3) were isolated from Leucas zeylanica. The structure of the new compound was elucidated using comprehensive spectroscopic methods. Compound 1 showed significant inhibitory activity against α-glucosidase (IC50 value of 0.85 ± 0.12 µM).


Subject(s)
Glucosides/isolation & purification , Glycoside Hydrolase Inhibitors/isolation & purification , Lamiaceae/chemistry , Triterpenes/isolation & purification , Glucosides/chemistry , Glycoside Hydrolase Inhibitors/pharmacology , Lamiaceae/metabolism , Molecular Structure , Plant Extracts/chemistry , Plant Extracts/pharmacology , Triterpenes/chemistry , alpha-Glucosidases/drug effects , alpha-Glucosidases/metabolism
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