[On the technique of examination in ERCP, EPT with stone extraction and PTC from the radiologist's viewpoint (author's transl)]. / Zur Untersuchungstechnik bei ERCP, EPT mit Steinextraktion und PTC aus radiologischer Sicht.

Based on the empirical data of more than 2500 examinations we report on the technique of the endoscopic retrograde cholangio- and pancreaticography (ERCP), the endoscopic papillotomy (EPT) with calculus extraction and also the percutaneus transhepatic cholangiography (PTC) from the radiologic point of view. The essential tasks of the radiologist are the clarifying of the position of the probe, the quick diagnosis and the making of valid x-ray photographs. For this purpose the knowledge about an optimal technique of examination is the prerequisite. By this the experienced radiologist is an important partner of the gastroenterologist. He helps to avoid complications for the patient.

Lyophilization of sincalide and correlation of headspace relative humidity with product stability.

An optimum freeze-drying cycle was developed for use with industrial equipment in the processing in vials of a product degraded by traces of moisture. The relative humidity of the headspace gas of the vials, which contained only 5 microgram of active ingredient, was monitored by a GC method and was then correlated with product stability.

GLC determination of 7-chloro-5,11-dihydrodibenz[b,e][1,4]-oxazepine-5-carboxamide in serum or plasma.

This report describes the isolation, derivative formation, GLC, and quantitation of unmetabolized 7-chloro-5,11-dihydrodibenz[b,e][1,4]oxazepine-5-carboxamide (I) in blood serum or plasma. Carbamazepine is used as the internal standard to compensate for losses of I during extraction and handling. Essentially complete recovery (100 +/- 6%) was demonstrated over a concentration range of 1-30 mug of I/ml of serum.