Oscillometric brachial mean artery pressures are higher than intra-radial mean artery pressures in intensive care unit patients receiving norepinephrine.

BACKGROUND: Norepinephrine is frequently used in intensive care unit (ICU) patients to raise and maintain an adequate mean arterial pressure (MAP). Conflict arises as to which MAP should guide vasopressor dose, as oscillometric MAP in the brachial artery often diverges from intra-radial MAP. We wanted to estimate the magnitude of this difference in ICU patients receiving norepinephrine, and to see whether the patient age, norepinephrine dose, age of radial catheter, ventilation treatment or severity of illness influenced the difference. METHODS: Prospective observational study comparing oscillometric MAP and intra-radial MAP performed in a central hospital-based surgical ICU during the period from February 2002 through to October 2003. Sixty-eight consecutive patients who received a norepinephrine infusion to maintain MAP above 70 mmHg were included. The mean arterial blood pressure was measured both oscillometrically and in the ipsilateral radial artery. RESULTS: Oscillometric MAP was on average 6.6 mmHg higher (95% CI 5.3-7.9) than intra-radial MAP in the 134 sets of measurements (P < 0.001). The patient's age (P = 0.319), norepinephrine dosage (P = 0.959) the age of the radial catheter (P = 0.992) were not significant. The difference in MAP was marginally greater in ventilated patients (P = 0.061) and significantly greater as the simplified acute physiology score (SAPS) score increased (P = 0.022). CONCLUSIONS: MAP measured oscillometrically over the brachial artery directly in the radial artery gave different results in an ICU population receiving norepinephrine. In more than one of four patients this difference is so large, and increases with illness severity, that the selection of any one method would influence treatment.

[Cemented versus cementless revision femoral stems using morselized allograft--a prospective, randomized study with 5 years follow-up]. / Zementierte versus unzementierte Revisions-Hüftarthroplastik mit verdichtetem Knochenallograft--Prospektiv randomisierte Vergleichsstudie mit Jahres-Follow-up.

BACKGROUND: There are only few studies on hip revision using the impaction grafting technique. Furthermore, data on cementless femoral stems as compared to cemented and polished femoral stems are lacking. We wanted to determine whether cementless femoral stems were equally good in preserving bone mineral density around the femoral stem and in functional outcome. METHOD: Consecutively 14 patients needing hip revisions for aseptic loosening in the stem with bone stock deficiency Paparowsky grade II were randomized into two groups intraoperatively. Morselized fresh-frozen bone allografts were impacted in both groups. The cemented group received polished Landos Fjord-CrCo stems and the uncemented group received the hydroxyapatite-coated Landos Corail-Titan stems. The dual energy X-ray absorptiometry was used to measure bone mineral density around the femoral stem according to Gruen zones. Function was measured by Merle d'Aubigné score. Patients were controlled at 0.5, 3, 6, 9, 12, 18, 24, 36 and 60 months postoperatively. RESULTS: There was no statistical difference between the BMD loss in the cemented vs. the uncemented group. The BMD loss was between 0-10 % in distal Gruen zones and was between 10-20 % in proximal Gruen zones. Functional scores were similar and reached a plateau of 16 in the Merle d'Aubigné score after 6 months. CONCLUSIONS: Cemented technique in hip revisions using morselized bone allograft is as good as uncemented technique in preserving BMD measured by the DEXA method and restoring function in a 5 years follow-up.

High survival in out-of-hospital cardiopulmonary resuscitation--7 years' incidence according to the Utstein template in a small town in Northern Norway.

Core data according to the Utstein template was compiled from all out-of-hospital resuscitations in the city of Bodø, Northern Norway, over 7 years (1992-98). Out of a population of 34,500, 149 resuscitations were attempted. A cardiac aetiology was present in 123 patients and their median age was 72.1 years. Eighteen of the 96 patients having suffered a witnessed arrest of cardiac origin were alive after 1 year (18.8%). Fifteen had the best cerebral performance score (scale 1-5) and three had a score of 2. Survival among all resuscitated patients (149) was 18.8% also, giving a number of 62 attempted resuscitations and 11.2 survivors per 100,000 inhabitants per year, respectively. Thirty-three per cent of witnessed cardiac arrests with ventricular fibrillation or ventricular tachycardia survived to discharge, but only 7% with asystole. When the arrest was witnessed, median response time was 5 minutes, and was 3 minutes for the survivors. To our knowledge, this is the highest survival of out-of-hospital arrests in Scandinavia reported so far, and is chiefly explained by short turnout distances.