ABSTRACT
INTRODUCTION: The Sydney system proposal for the study and reporting of lymphadenopathy by fine-needle aspiration (FNA) constitutes one of the first attempts to standardize this procedure. Here, we review its applicability. MATERIALS AND METHODS: A retrospective study in which all ultrasound-guided FNAs (USFNAs) of superficial lymphadenopathy (palpable or not) performed by interventional pathologists in 2 specialized hospital centers were quantified over 2 years. The procedure was systematized, and the diagnoses were reclassified according to the Sydney system categories. RESULTS: We analyzed 363 USFNAs of lymphadenopathies. The distribution of cases by categories was as follows: insufficient (n = 13; 3.58%), benign (n = 208; 57.30%), atypia of uncertain significance (n = 7; 1.93%), suspicious (n = 21; 5.79), and malignant (n = 114; 31.40%). The risks of malignancy calculated for categories I, II, III, IV, and V were 27%, 3%, 50%, 100%, and 100%, respectively. CONCLUSION: The implementation of the Sydney system allows the systematization and standardization of the lymph node FNA methodology, with increased efficacy and efficiency. Assimilating the recommendations enables the qualification of the diagnostic procedure.
Subject(s)
Image-Guided Biopsy , Lymph Nodes/pathology , Lymphadenopathy/pathology , Ultrasonography, Interventional , Adolescent , Adult , Aged , Aged, 80 and over , Biopsy, Fine-Needle , Child , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Reproducibility of Results , Retrospective Studies , Spain , Young AdultABSTRACT
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Subject(s)
Pathology/ethics , Pathology/history , Pathology/methods , Pathology Department, Hospital/trends , Cell Biology/organization & administration , Cell Biology/standards , Pathology/organization & administration , Pathology/standards , Pathology Department, Hospital/organization & administration , Pathology Department, Hospital/standards , Pathology Department, Hospital , Biopsy, Fine-Needle/methods , Biopsy, Fine-Needle/trendsABSTRACT
History A 61-year-old man with no relevant medical history was admitted to the emergency department with symptoms of congestive heart failure and a 1-week history of chest pain, progressive dyspnea, abdominal swelling, bipedal edema, and anorexia. Laboratory test results, including complete blood count and electrolyte, creatinine, creatine phosphokinase, and troponin T levels were normal. Electrocardiographic findings were unremarkable. Initial chest radiography showed an enlarged heart with bilateral pleural effusion. Transthoracic echocardiography revealed an irregular right atrial mass and moderate to severe pericardial effusion. The patient subsequently underwent computed tomography (CT) of the chest, abdomen, and pelvis followed by cardiac magnetic resonance (MR) imaging for further evaluation of the atrial mass. Because of the suspected diagnosis, conventional radiography of the skeleton was performed.
Subject(s)
Histiocytosis, Langerhans-Cell/diagnostic imaging , Myocardium/pathology , Tomography, X-Ray Computed , Histiocytosis, Langerhans-Cell/pathology , Humans , Magnetic Resonance ImagingSubject(s)
Carcinoma, Hepatocellular/secondary , Laryngeal Neoplasms/secondary , Liver Neoplasms/pathology , Adenoma, Oxyphilic/diagnosis , Antineoplastic Agents/therapeutic use , Biopsy, Fine-Needle , Carcinoma, Hepatocellular/diagnosis , Carcinoma, Hepatocellular/drug therapy , Carcinoma, Hepatocellular/surgery , Combined Modality Therapy , Diagnosis, Differential , Diagnostic Imaging , Embolization, Therapeutic , Humans , Laryngeal Neoplasms/diagnosis , Laryngeal Neoplasms/drug therapy , Laryngeal Neoplasms/surgery , Laryngectomy , Liver Neoplasms/diagnosis , Liver Neoplasms/drug therapy , Liver Neoplasms/therapy , Male , Middle Aged , Niacinamide/analogs & derivatives , Niacinamide/therapeutic use , Phenylurea Compounds/therapeutic use , Sorafenib , Thyroid Neoplasms/diagnosis , ThyroidectomySubject(s)
Humans , Male , Female , Neoplasm Metastasis/diagnosis , Neoplasm Metastasis/physiopathology , Laryngeal Neoplasms/complications , Laryngeal Neoplasms/surgery , Carcinoma, Hepatocellular/complications , Carcinoma, Hepatocellular/diagnosis , Neoplasm Metastasis , Larynx/pathology , Larynx , Laryngeal Neoplasms/physiopathology , Laryngeal Neoplasms , Carcinoma, Hepatocellular/physiopathology , Carcinoma, Hepatocellular/surgery , Carcinoma, HepatocellularABSTRACT
El carcinoma de los conductos colectores (CCC) es una entidad poco frecuente que representa menos del 1 por ciento del total de las neoplasias renales. La mayoría de los casos publicados han sido descritos como tumores de gran agresividad y de mal pronóstico. Presentamos un caso de un CCC de bajo grado y de pronóstico favorable al que se le realizó una nefrectomía radical sin evidencia de recidiva tumoral tras dos años de seguimiento (AU)