ABSTRACT
Ketamine was given together with premedication (droperidol + pethidine + atropine) for general anaesthesia in 36 children during pneumoencephalography. Most children (26) had epilepsy. No significant cardiovascular and respiratory disturbances were observed during and after anaesthesia. This proposed method of anaesthesia in children is sufficient for short-lasting diagnostic procedures, particularly for pneumoencephalography.
Subject(s)
Anesthesia, General , Ketamine , Pneumoencephalography , Adolescent , Anesthesia, Intravenous , Child , Child, Preschool , Female , Humans , Infant , Injections, Intramuscular , Intracranial Pressure/drug effects , Ketamine/adverse effects , Ketamine/pharmacology , Male , Preanesthetic MedicationABSTRACT
In 43 patients the effect of low concentrations of methoxyflurane on the renal function was studied. The blood levels of urea, creatinine, uric acid, sodium and potassium, and specific weight of urine was determined. It was found that the anaesthetic technique used and methoxyflurane concentrations in the range of 0.2-0.5 vol% caused no abnormalities in renal function. It seems that methoxyflurane in low concentrations (0.2-0.5 vol%) is the best method of anaesthesia with this agent, with the simultaneous use of a nitrous oxide-oxygen mixture and controlled ventilation.
Subject(s)
Kidney/drug effects , Methoxyflurane/pharmacology , Adult , Creatinine/blood , Female , Humans , Kidney/physiology , Male , Methoxyflurane/administration & dosage , Middle Aged , Urea/blood , Uric Acid/bloodABSTRACT
In 37 patients the effect of neostigmine administered in divided doses (0.1 to 0.5 mg) on the dynamics of decurarization was studied by evaluating the tidal volume and respiratory rate. It was found that doses of neostigmine caused a continuous rise in tidal volume. Normalization of the tidal volume depended on the dose administered. The rate of decurarization depended also on the duration of the operation and the time of administration of the last d-tubocurarine dose. The proposed method of decurarization enables a safe reversal of d-tubocurarine effect to be obtained with a small dose of neostigmine.
