ABSTRACT
In the title compound, C(16)H(19)ClN(2)O(4), the pyridine ring is nearly planar, the piperidine ring is non-planar and the cyclohexane ring adopts a screw-boat conformation. The carboxylate group makes a dihedral angle of 80.9 (2) degrees with the least-squares plane through the cyclohexane ring.
Subject(s)
Cholinergic Agonists/chemistry , Phenanthrolines/chemistry , Crystallography, X-Ray , Molecular Conformation , Molecular StructureABSTRACT
The title compound, C(19)H(16)O, crystallizes with two molecules of opposite chirality in the asymmetric unit. In both molecules, the naphthalene and cyclopentanone moieties are individually planar. The two cyclopentane rings adopt envelope conformations, while the cyclohexane ring adopts a boat conformation.
Subject(s)
Coumarins/chemistry , Fluorenes/chemistry , Coumarins/chemical synthesis , Crystallography, X-Ray , Molecular Structure , StereoisomerismABSTRACT
By characterizing isomorphism in reciprocal space [i.e. diffraction data sets are isomorphous if they have the same geometry (the same reciprocal-lattice unit cell) and the same symmetry] it is shown that the diffraction data of a native protein and of its heavy-atom derivatives, the calculated data of a partial structure and the observed data of its associated complete structure, and the Friedel-pair data of an anomalously scattering crystal structure all belong to the more general class of isomorphous data sets. Their joint probability distributions for two- and three-phase structure invariants are shown to be isomorphous: they have the same functional form and differ only in individual atomic scattering factors. General joint probability distributions, which can be used for any isomorphous data pairs, are presented.
