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1.
Vet J ; 238: 22-26, 2018 08.
Article in English | MEDLINE | ID: mdl-30103912

ABSTRACT

Enteropathy associated with sand accumulation in the large colon of horses has been reported worldwide. Intestinal sand accumulations are commonly treated medically, but randomised controlled clinical trials on horses are scarce. This prospective study evaluated the efficacy of an enterally administered combination of psyllium and magnesium sulphate (MgSO4) for the removal of large colonic sand accumulations in horses without clinical signs of acute colic. The two groups comprised 20 untreated control horses and 20 horses treated with 1g/kg bodyweight (bwt) of psyllium and 1g/kg bwt of MgSO4 administered by nasogastric intubation once daily for 4 days. Both groups had no access to soil during the study period. The amounts of accumulated sand were evaluated radiographically before and after treatment. Significantly more treated horses cleared their sand accumulations than horses in the control group. This clearance was determined by observing the estimated quantity by area of sand remaining in the large colon (P<0.001) and by comparing the numbers of successfully treated horses (P=0.004) between the two groups after 4days of treatment. However, there were unexplained individual variations in the clearance of sand accumulation.


Subject(s)
Cathartics/pharmacology , Colon/drug effects , Horse Diseases/drug therapy , Magnesium Sulfate/pharmacology , Psyllium/pharmacology , Animals , Colic , Colon/pathology , Horses , Intestinal Obstruction/drug therapy , Intestinal Obstruction/veterinary , Prospective Studies , Silicon Dioxide
2.
Equine Vet J ; 50(6): 865-869, 2018 Nov.
Article in English | MEDLINE | ID: mdl-29518268

ABSTRACT

BACKGROUND: In dogs, due to better alignment with the aortic outflow, the subcostal (SC) transducer site provides greater Doppler-derived velocities than those obtained from the left parasternal view. The feasibility of this imaging approach has never been described in equine echocardiography. OBJECTIVES: The objective of this study was to evaluate the feasibility of the SC view in newborn foals and compare aortic two-dimensional and Doppler-derived velocity measurements with those of standard parasternal long-axis (LAX) views. STUDY DESIGN: A prospective observational study. METHODS: Twenty-three newborn healthy Standardbred and Warmblood foals, aged from 7 h to 6 days, underwent transthoracic two-dimensional (2DE), M-mode and Doppler echocardiography that was performed in lateral recumbency. Right and left parasternal long-axis (R-LAX, L-LAX) and SC views were obtained to perform 2DE and Doppler assessments of the aortic valve (AoV). Aortic diameter at the sinus of Valsalva (AoS D) was measured from R-LAX and SC images. Aortic maximal velocity (AoV Velmax ), velocity time integral (AoV VTI) and pressure gradient (AoV PG) were obtained by pulsed wave Doppler spectra from SC and L-LAX views. RESULTS: The SC view was feasible in all foals. No significant difference was found in AoS D between different views (P = 0.06), and no significant correlation was detected for bodyweight (BW). AoV Velmax , VTI and PG obtained from the SC view were greater than from the L-LAX view (P<0.0001, P = 0.0001 and P<0.0001 respectively), especially in foals with lower BW. MAIN LIMITATIONS: The order of the transducer site was not randomised among foals, and the observer was not blinded during offline measurement. CONCLUSIONS: The SC view can be easily obtained in recumbent newborn foals and provides optimal alignment with aortic outflow, leading to more reliable Doppler flow velocity than the conventional L-LAX view. Further investigations of the potential use of this view in Doppler estimation of aortic outflow and cardiac assessment of sick foals are recommended.


Subject(s)
Animals, Newborn/anatomy & histology , Aorta/diagnostic imaging , Aorta/physiology , Echocardiography, Doppler/veterinary , Horses/anatomy & histology , Animals , Animals, Newborn/physiology , Aortic Valve/diagnostic imaging , Aortic Valve/physiology , Blood Flow Velocity/veterinary , Echocardiography, Doppler/methods , Feasibility Studies , Female , Horses/physiology , Male , Prospective Studies
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