1.
Clin Case Rep
; 1(2): 50-3, 2013 Dec.
Article
in English
| MEDLINE
| ID: mdl-25356211
ABSTRACT
KEY CLINICAL MESSAGE: Maternal serum screening-positive patient had prenatal diagnosis with amniotic fluid, which showed inconsistent results between interphase fluorescence in situ hybridization (three signals of 21q22.13-21q22.2) and G-banding analysis (46,XY). Further analyses proved that the fetus had extremely complex rearrangements of chromosome 21, including the interstitial duplication of Down syndrome critical region.