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Ned Tijdschr Geneeskd ; 162: D2577, 2018.
Article in Dutch | MEDLINE | ID: mdl-29543146

ABSTRACT

The Netherlands Medicines Evaluation Board (MEB) was recently informed about a serious pipamperone overdose in a 6-year-old boy, which happened because the boy was given the medication in streams rather than in drops. This article describes the use of drops in pharmaceutical patient care and explains why the MEB has maintained marketing authorization for the product on the basis of currently available information. The MEB urgently requests the healthcare professional groups to report all problems concerning drug use to the Netherlands Pharmacovigilance Centre Lareb, and the Portal for Patient Safety; this is the only way in which it can be verified whether incidental medication errors are actually, and continue to be, incidental.


Subject(s)
Administration, Oral , Butyrophenones/administration & dosage , Drug Overdose/etiology , Medication Errors/adverse effects , Serotonin Antagonists/administration & dosage , Adverse Drug Reaction Reporting Systems , Butyrophenones/adverse effects , Child , Dosage Forms , Drug Overdose/prevention & control , Humans , Male , Medication Errors/legislation & jurisprudence , Medication Errors/prevention & control , Netherlands , Pharmacovigilance , Serotonin Antagonists/adverse effects
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