Generalized subcutaneous emphysema caused by concurrent cricoid cartilage fracture and cricotracheal detachment in a German shepherd dog.

A dog was presented with history of progressive generalized subcutaneous emphysema and exercise intolerance secondary to dog fight. Radiographic evaluation confirmed extensive subcutaneous emphysema, pneumomediastinum and pneumoretroperitoneum. Surgical exploration revealed cricoid cartilage longitudinal fracture and cricotracheal detachment. The fractured cartilage was sutured and the cricoid cartilage and trachea was approximated using interrupted sutures. Concurrent cricoid cartilage fracture and cricotracheal detachment has not been reported in veterinary literature, which should be considered in any case of subcutaneous emphysema secondary to extrinsic laryngeal trauma.

The healing effect of bioglue in articular cartilage defect of femoral condyle in experimental rabbit model.

BACKGROUND: The full-thickness articular cartilage defects of knee have a poor healing capacity that may progress to osteoarthritis and need a knee replacement. This study determines the healing effect of bioglue in fullthickness articular cartilage defect of femoral condyle in rabbit. METHODS: Forty-eight male rabbits were randomly divided into four equal groups. In group A, 4 mm articular cartilage defects were created in the right and left medial femoral condyles. Then a graft from xiphoid cartilage was transferred into the defect together with a designed bioglue and the knees were closed. In group B, an articular cartilage defect was created identical to group A, but the defect size was 6 mm. In group C, 4 and 6 mm articular cartilage defects were created in the right and left medial femoral condyles respectively. The graft was transferred into the defect and the knees were stitched. In group D, articular cartilage defects were created similar to group C, just filled with bioglue and closed. The rabbits were euthanized and subgroups were defined as A1, B1, C1 and D1 after 30 days and A2, B2, C2 and D2 after 60 days. The cartilages were macroscopically and histologically investigated for any changes. RESULTS: Microscopic and macroscopic investigations showed that bioglue had a significant healing effect in the femoral condyle. CONCLUSION: Addition of bioglue can effectively promote the healing of articular cartilage defects.

The relationship between serum level of thyroid hormones, trace elements and antioxidant enzymes in dromedary camel (Camelus dromedarius).

Thyroid hormones might be able to regulate the activities of superoxide dismutase (SOD), catalase and glutathione peroxidase (GPX). The role of thyroid hormones in metabolic pathways and antioxidant enzyme activities are well known in many species. Nevertheless, there is no report describing probable relationship between thyroid hormones status, erythrocyte antioxidant enzymes and serum profiles of trace elements. This study was undertaken to investigate the relationship between these parameters in Iranian dromedary camels. Blood samples were taken from the jugular vein of 30 clinically healthy Iranian dromedary camels under aseptic conditions during 6 consecutive days of summer. The serum was analyzed for serum profile of thyroid hormones, trace elements, SOD and GPX activity. There were no significant differences in serum thyroid hormones, serum level of zinc (Zn), copper (Cu), manganese (Mn), iron (Fe), selenium and antioxidant enzymes in different days (P > 0.05). There was a significant negative correlation between SOD and Fe (P < 0.01, r = -493). There was no significant correlation between other parameters. In case of copper deficiency likewise the present study, the copper was used to produce more SOD, so there was a decrease in Fe transportation, and it might be a cause of decrease in Fe amount. On the other hand, a relatively small quantity of Fe is present in tissue myoglobin, catalase, peroxidases, and cytochromes. So it might be another cause of decrease in Fe amount. The explanation for these finding is not possible at this moment and further investigations are needed to interpret these changes.

Studies on correlations among parasitaemia and some hemolytic indices in two tropical diseases (theileriosis and anaplasmosis) in Fars province of Iran.

This study was carried out in two observational clinical studies. Study 1 comprised 50 adult crossbred cattle naturally infected by Theileria annulata. Infected animals were divided into 4 subgroups with different parasitaemia (<1%, 1-3%, 3-5% and >5%). Study 2 comprised 20 adult crossbred cattle naturally infected by Anaplasma marginale. Infected animals were divided into 3 subgroups with different parasitaemia (<10%, 10-20% and 20-30%). In study 1, a significant negative correlation (P<0.001) was observed between parasitaemia and superoxide dismutase (SOD). Positive correlations (P<0.001) were observed between parasitaemia and lactate dehydrogenase (LDH) and mean corpuscular fragility (MCF). In study 2 positive correlations (P<0.05) were observed among parasitaemia and MCF and LDH activity. SOD activity had a negative correlation with parasitaemia in cattle with parasitaemia lower than 10% but no significant correlation (P>0.05) was observed between SOD activity and parasitaemia in cattle with 10-20 and 20-30% parasitaemia. In comparison of both studies we came to the conclusion that in theileriosis as the severity of disease increased the anaemia, MCF and LDH activity increased and SOD activity decreased at any parasitaemia, but in anaplasmosis the anaemia, MCF and LDH activity increased at any parasitaemia but SOD activity decreased only in early but not in advanced stages of disease.