The Impact of Individual Mentored Career Development (K) Awards on the Research Trajectories of Early-Career Scientists.

PURPOSE: This analysis examined the role of a National Institutes of Health (NIH) individual Mentored Career Development Award (K01, K08, K23) on launching and sustaining independent research careers for early-career scientists, and investigated the effects of these awards during and after the doubling of the NIH budget. METHOD: The authors used grants data from the NIH covering the period 1990 through 2016, and compared success in receipt of R01 equivalent awards (R01 Eq.) and Research Project Grants (RPGs) for K awardees and K applicants who did not receive funding. The analysis combined regression discontinuity design with coarsened exact matching, and regression. RESULTS: Overall, receipt of K award was associated with a 24.1% increase in likelihood of first independent NIH award (P < .01), and a larger number of R01 Eq. and RPG awards. After accounting for first major independent awards, K awards were uncorrelated with receiving second major independent research awards. Comparing different funding periods, K01 awards were predictive of subsequent R01 Eq. and RPG awards after but not during the NIH doubling, K08 awards were predictive only during the NIH doubling, and K23 awards were predictive during both periods. CONCLUSIONS: Receipt of Mentored Career Development Awards was linked to increased likelihood that early-career scientists successfully transitioned to an independent research career. These findings indicate that extending funding to additional K award applicants with meritorious scores could significantly strengthen the pipeline of biomedical researchers. In addition, enhancing K awards may be relevant to sustaining research careers for clinician scientists.

Examining trends in the diversity of the U.S. National Institutes of Health participating and funded workforce.

Here, we use recent U.S. National Institutes of Health (NIH) data to document trends in the NIH-funded workforce over time. Consistent with previous studies that were initiated by NIH, we find that the number of scientists funded on competing R01-equivalent (R01 Eq.) and research project grants (RPGs) increased 2-5% per year between 2009 and 2016. Primary beneficiaries of this growth were experienced investigators (Exp), whereas the share of funding awarded to early-stage investigators (ESIs) and new investigators (NIs) declined. The decline occurred even after NIH instituted the New and Early-Stage Investigator policy in 2009. When we evaluate the investigator pool, we find that women and racial and ethnic minorities represent a higher percentage of NIs and ESIs relative to Exp. Thus, trends of diminishing support for NIs and ESIs may negatively impact the diversity of the current and future biomedical research workforce. We find some recent gains among women and Hispanics as part of the applicant and awardee pool for both R01 Eq. and RPGs, but significant, large gaps persist among nationally underrepresented racial minorities. Our findings suggest a need to prioritize investments and support of ESIs and NIs, groups in which women and racial and ethnic minorities represent a larger proportion of the applicant pool, to enhance diversity in the NIH-funded workforce.-Nikaj, S., Roychowdhury, D., Lund, P. K., Matthews, M., Pearson, K. Examining trends in the diversity of the U.S. National Institutes of Health participating and funded workforce.

School personnel smoking, school-level policies, and adolescent smoking in low- and middle-income countries.

OBJECTIVES: This paper examines the link between personnel and teacher smoking on school grounds, and student smoking in 62 low-income and middle-income countries. METHODS: We use a two-part model to estimate the effect of smoking by school personnel on youth smoking. In the first part, we model the decision to smoke for all students, using a linear probability model. In the second part, we estimate cigarette consumption among smokers. We employ country fixed effects to address country-level time-invariant unobservable factors and control for an array of local-level variables to address local-level heterogeneity. RESULTS: We find that smoking by personnel and teachers on school grounds is associated with higher smoking prevalence among all youths, and higher cigarette consumption among female smokers. Our findings suggest that consumption among female smokers is primarily affected by smoking among female personnel, and that younger personnel/teachers appear to be more influential in determining behaviours among young people. In addition, we find that smoking restrictions on staff are associated with reductions in average consumption among female students. CONCLUSIONS: Low-income and middle-income countries may reduce smoking among young people by banning smoking for teachers and school personnel on school grounds.

Alcohol consumption and social network ties among adolescents: evidence from Add Health.

Although many studies have estimated the influence of peers on risky health behaviors, few have estimated the gains that adolescents receive from such behaviors, particularly in terms of social payoffs for complying with peer behavior. In this paper, we explore the extent to which alcohol consumption increases popularity of adolescents. Using data from a nationally-representative sample of adolescents, we estimate endogeneity-corrected models with school-level fixed effects to identify the effect of alcohol consumption on social network ties. We find that alcohol consumption leads to an increase in popularity, with the largest gains experienced by white males and females. Our results provide new evidence on the motivation behind adolescent drinking and have important implications for substance abuse interventions.

The effect of prices on cigarette use among youths in the global youth tobacco survey.

INTRODUCTION: We estimated the impact of cigarette prices on youth smoking in 38 countries with the Global Youth Tobacco Survey. METHODS: We used a 2-part model of cigarette demand. In the first part, we estimated the impact of prices on the decision to smoke. Conditional on smoking, we then estimated the effect of price on the number of cigarettes smoked. We employed 2-way fixed effects to address country-level time-invariant heterogeneity and controlled for an array of local-level variables to address local-level heterogeneity. RESULTS: The estimated total price elasticity is -1.5 for a sample that contains both high-income and low- and middle-income countries. Constraining the sample to only low- and middle-income countries, we found a total price elasticity of -2.2, suggesting that smoking among youths in low-income countries is more responsive to cigarette price changes. CONCLUSION: Cigarette price increases are highly effective in reducing smoking prevalence and consumption among youths globally and particularly among youths in low- and middle-income countries.