Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 53
Filter
Add more filters










Publication year range
1.
Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med ; 28(Special Issue): 741-747, 2020 Aug.
Article in Russian | MEDLINE | ID: mdl-32856818

ABSTRACT

The article presents the results of the author's research that determines the degree of influence of monotonous (monotonous) labor processes on the drivers (and their assistants) of traction rolling stock of railway transport. Information is collected in order to develop a set of measures to overcome the monotony of work, improve the quality of working life and psychophysiological health of employees, and as a result, ensure traffic safety, improving the safety system for drivers and improving the quality of passenger transport.


Subject(s)
Occupational Stress , Railroads , Humans , Stress, Psychological
2.
Khirurgiia (Mosk) ; (5): 77-81, 2019.
Article in Russian | MEDLINE | ID: mdl-31169824

ABSTRACT

Treatment of complicated giant duodenal ulcers is one of the most difficult problems in abdominal surgery. Simultaneous course of diabetes mellitus and giant duodenal ulcer has clinical features and requires correction of the treatment. It is presented case report that may be useful regarding accumulation of knowledge about comorbid course of these pathologies. The patient 58-year old was urgently delivered with signs of gastrointestinal bleeding, ulcerative anamnesis for 15 years, diabetes mellitus type 2 for 8 years. Gastroduodenoscopy revealed chronic giant (2.5×3.5 cm) duodenal ulcer complicated by bleeding and subcompensated pyloric stenosis. Endoscopic hemostasis included drug injection and argon-plasma coagulation. Recurrent bleeding occurred after 22 hours. It was performed Billroth II procedure with resection of 2/3 of the stomach and manual formation of 'difficult' duodenal stump. Cicatricial ring was used as a frame for the stump. Postoperative period was uneventful, patient was discharged after 14 days. This clinical case demonstrates the need for more active surgical strategy in patients with diabetes mellitus and reliability of the proposed method of 'difficult' stump forming.


Subject(s)
Diabetes Mellitus, Type 2/complications , Duodenal Ulcer/surgery , Peptic Ulcer Hemorrhage/surgery , Pyloric Stenosis/surgery , Cicatrix/etiology , Cicatrix/surgery , Duodenal Ulcer/complications , Duodenal Ulcer/diagnosis , Duodenum/pathology , Duodenum/surgery , Gastroenterostomy , Humans , Middle Aged , Peptic Ulcer Hemorrhage/diagnosis , Peptic Ulcer Hemorrhage/etiology , Pyloric Stenosis/diagnosis , Pyloric Stenosis/etiology , Reproducibility of Results
3.
Biull Eksp Biol Med ; 115(5): 523-5, 1993 May.
Article in Russian | MEDLINE | ID: mdl-8043843

ABSTRACT

The age dynamics of albino rat kidney cell proliferation in conditions of compensatory hypertrophy and influence of endogenous inhibitors on this process have been studied. The lack of influence of repeated injection of inhibitors on kidneys cell division of 1-month old rats has been shown, while the level of kidney proliferation of 3-month old rat and 12-month old rat decreased of about 50% and of 24-month old rat decreased of about 34%.


Subject(s)
Growth Inhibitors/physiology , Kidney/pathology , Aging/pathology , Animals , Cell Division/physiology , DNA/biosynthesis , Hypertrophy/metabolism , Hypertrophy/pathology , Kidney/metabolism , Rats , Rats, Wistar , Time Factors
7.
Fiziol Zh (1978) ; 36(5): 11-6, 1990.
Article in Russian | MEDLINE | ID: mdl-2272385

ABSTRACT

Modern approaches to lifespan prolongation of laboratory animals are considered. Calorie-deficient diet increasing lifespan, leads to essential hormonal shifts, to changes in the activity of genome, protein biosynthesis. These mechanisms determine lifespan prolongation.


Subject(s)
Life Expectancy , Aging/genetics , Aging/metabolism , Animals , Energy Intake/physiology , Hormones/metabolism , Protein Biosynthesis
10.
Fiziol Zh (1978) ; 36(1): 60-5, 1990.
Article in Russian | MEDLINE | ID: mdl-2108878

ABSTRACT

It is studied how long-term periodical calorie-insufficient and growth-restraining nutrition promoting appreciable life prolongation in the Wistar-line albino rats influences the lipid metabolism. It is shown that diet has an essential influence on the levels of phospholipids, cholesterol, neutral lipids, fatty acids in different tissue cells. The age specificity is observed in all the studied tissue cells. The lipid composition of cells in aged rats with prolonged life is similar to that of young animals of control group.


Subject(s)
Adipose Tissue/metabolism , Animal Nutritional Physiological Phenomena , Intestine, Small/metabolism , Lipid Metabolism , Liver/metabolism , Protein-Energy Malnutrition/metabolism , Age Factors , Animal Feed , Animals , Liver/pathology , Male , Rats , Rats, Inbred Strains
11.
Biull Eksp Biol Med ; 108(9): 287-9, 1989 Sep.
Article in Russian | MEDLINE | ID: mdl-2558740

ABSTRACT

It was discovered that there is sphingomyelinase activity in the rat liver nuclei. The maximum of enzyme activity is at pH 7.1. The data obtained demonstrated that the main part of sphingomyelinase is located in the nuclear membrane. Comparison of sphingomyelinase activity in cell nuclei, liver and brain homogenates shows high level of enzyme activity in the nuclei. The authors discuss possible participation of sphingomyelinases in changes of phospholipids composition in nuclear structure under different functional activity of cell nuclei.


Subject(s)
Brain/enzymology , Cell Nucleus/enzymology , Liver/enzymology , Phosphoric Diester Hydrolases/metabolism , Sphingomyelin Phosphodiesterase/metabolism , Animals , Hydrogen-Ion Concentration , Male , Rats , Sphingomyelin Phosphodiesterase/analysis
12.
Fiziol Zh (1978) ; 35(3): 91-8, 1989.
Article in Russian | MEDLINE | ID: mdl-2661274

ABSTRACT

Some major pathways of lipid metabolism are under control of thyroid hormones. Thyroxine changes the lipid composition of different cell membranes. Modification of thyroid hormone metabolism during ontogenesis is one of the reasons of changes in lipid composition and function of cell nuclei and its other structures. Atherosclerosis and obesity may be a result of the thyroid dysfunction and modulation of the cellular lipid metabolism.


Subject(s)
Lipid Metabolism , Thyroxine/physiology , Triiodothyronine/physiology , Animals , Cell Membrane/metabolism , Cell Membrane Permeability , Homeostasis , Humans , Rats , Subcellular Fractions/metabolism
14.
Ukr Biokhim Zh (1978) ; 60(1): 85-90, 1988.
Article in Russian | MEDLINE | ID: mdl-3363680

ABSTRACT

The possible influence of the type of dietary fat on quantitative changes of different lipids in microsomes, nuclei and chromatin in hepatic cells of albino rats in ontogenesis was studied. While the type of diet had no significant influence on the levels of different phospholipids and fatty acids of nuclei, the type of dietary fat exerted definite effect on the levels of whole phospholipids, cholesterol of microsomes, nuclei and fatty acids of chromatin. The age specificity was observed in nuclear structures.


Subject(s)
Aging/metabolism , Cell Nucleus/metabolism , Dietary Fats/pharmacology , Lipid Metabolism , Microsomes, Liver/metabolism , Animals , Male , Rats , Rats, Inbred Strains
17.
Biokhimiia ; 51(10): 1714-7, 1986 Oct.
Article in Russian | MEDLINE | ID: mdl-3778974

ABSTRACT

The metabolism of liver nuclear phospholipid acyl components of rats of various age was studied in vitro. It was found that the activity of phospholipases A1 and A2 in the nuclei sharply increased in animals aged 1-3 months, showing a decrease in 12- and 24-month-old animals. The incorporation of labeled arachidonic acid into nuclear phospholipids remained practically unchanged thereby. The age-specific fluctuations in the activity of nuclear phospholipids A1 and A2 may be one of possible reasons of changes in the fatty acid composition of nuclear lipids during ontogenesis.


Subject(s)
Aging/metabolism , Fatty Acids/metabolism , Liver/metabolism , Phospholipids/metabolism , Animals , Cell Nucleus/metabolism , Male , Rats , Rats, Inbred Strains
SELECTION OF CITATIONS
SEARCH DETAIL
...