[Structure of the metaepiphyseal growth plate cartilage in conditions of total isolation from cellular and humoral influences after its transplantation into soft tissues (an experimental study)].

The aim of this study was to determine the effect of a skeletal muscle on the cartilage of growth plate of metaepiphyseal explants of tubular bones of growing and mature Chinchilla rabbits (n = 18) under conditions of their isolation from cellular and humoral influences. In experimental animals, metaepiphyseal explants of metatarsal bones, containing growth plate, were sealed in polyethylene film and were placed, under local anesthesia, in the femoral muscles. One week later these grafts were removed and studied histologically. Despite the absence of the effects of biologically active substances and immunocompetent cells of the donor (foreign) organism, the exposure of the cartilage plate to the environment of the muscular tissue lead to some typical changes in its structure. The results obtained may indicate the susceptibility of the cartilage growth plates to the action of some distant factors, probably, of an electromagnetic nature. The detection of these factors is promising for the development of clinical methods of the stimulation of the damaged cartilage growth plates for the correction of bone deformities.

[Reparative bone regeneration after aseptic necrosis of the femoral head as influenced by 1-chloromethylsilatrane treatment].

The aim of this work was to study the effect of 1-chloromethyisilatranum on the processes of reparative bone regeneration in experimentally induced aseptic femoral head necrosis. Aseptic femoral head necrosis was modeled in 4 Chinchilla rabbits by destruction of spongy substance of femoral neck and cutting of ligamentum teres of its head. Rabbits of the experimental group were injected with 0.4 ml of 1% solution of 1-chloromethylsilatranum on postoperational days 5, 10, 15 and 20 into the damaged femoral head and close to the damaged joint. Animal were sacrificed by air embolism 5 weeks from the start of an experiment. Necrotic and repair processes in hip joints from damaged and intact sides were assessed radiologically and histologically prior to sacrifice. In rabbits of both control and experimental groups extensive aseptic necrosis of hip joints was found. The osseous tissue of damaged hip joints of experimental animals contained the chains of osteoblasts actively producing new bone matrix. Foci of bone regeneration were found both in the deep and peripheral regions of the epiphysis, which is indicative of active processes of bone repair. The results obtained suggest that administration of organic-silicon drug 1-chloromethylsilatranum stimulates (optimizes) the processes of repair osteogenesis following aseptic femoral head necrosis in experimental animals. Application of this preparation appears to be very promising.

[The differential diagnosis of posttraumatic ossifications in the area of the elbow joint in children]. / Differentsial'naia diagnostika posttravmaticheskikh ossifikatov v oblasti loktevogo sustava u detei.

Clinico-roentgenological observations of 64 patients aged from 4 to 14 years with posttraumatic ossifications in the elbow joint area, of whom 25 were operated upon, enabled the authors to compare the data obtained with the well-known signs of osteogenesis of another etiology. The case history and x-ray examinations are thought by the authors to be the most important methods allowing the nature of this osteogenesis to be differentiated. The main distinctive signs of the posttraumatic ossifications are the development of their roentgenological stages in the special chronological succession.

[Heterotopic ossification as a complication of fracture-dislocations of the forearm in children]. / Geterotopicheskaia ossifikatsiia kak oslozhnenie perelomovyvikhov predplech'ia u detei.

Under observation there were 59 patients ranging in age from 4 to 14 years with posttraumatic ossifications in the elbow joint areas. All the patients were given conservative treatment, 23 patients needed operative interventions on the elbow joint. Long-term results were studied at the period from 6 months to 8 years. Good and satisfactory functional results were noted in 96.8% of the patients after the conservative treatment. After the operative treatment good and satisfactory functional and anatomical results were obtained in 90% of the patients.

[The vascularization characteristics of free transplants of the growth zones of the long tubular bones (experimental studies)]. / Osobennosti vaskuliarizatsii svobodnykh transplantatov rostkovykh zon dlinnykh trubchatykh kostei (éksperimental'nye issledovaniia).

The authors have studied the process of revascularization of free transplants of growth zones of the bones transplanted heterotopically from greater trochanter of the femur onto the chest. The X-ray and histological data have shown the ingrowth of the vessels into autotransplants from the side of soft tissues of the recipient bed responsible for the growth of the epiphyseal cartilage.