Subject(s)
Dyspepsia/diagnosis , Adolescent , Anti-Ulcer Agents/therapeutic use , Child , Child, Preschool , Cisapride/therapeutic use , Diagnosis, Differential , Dyspepsia/drug therapy , Dyspepsia/physiopathology , Female , Helicobacter Infections/diagnosis , Humans , Male , Prospective Studies , Ranitidine/therapeutic useABSTRACT
Methylmethacrylate has been used as an external fixator on 52 bones in 36 children and adolescents. There were 36 osteotomies and 16 selected fractures of long bones. The application of the acrylic cement onto 229 half-pins was performed with the use of flexible plastic tubes, in all but two patients. Union in the desired position was achieved in 51 bones. Delayed union occurred in one and required internal fixation. In the rest of the cases, there were only a few minor complications. The methylmethacrylate appears to be a stable fixator for osteotomized and fractured bones in young patients. The method is practical, easily performed, and of low cost.
Subject(s)
External Fixators , Fracture Fixation , Fractures, Bone/surgery , Methylmethacrylates/therapeutic use , Adolescent , Bone Cements/therapeutic use , Child , Child, Preschool , Colloids/therapeutic use , External Fixators/adverse effects , Female , Femoral Fractures/surgery , Follow-Up Studies , Fracture Fixation/instrumentation , Fracture Fixation/methods , Humans , Humeral Fractures/surgery , Infant , Male , Methylmethacrylate , Postoperative Complications , Radius Fractures/surgery , Tibial Fractures/surgeryABSTRACT
The literature on clinical and roentgenographic findings of Proteus syndrome is reviewed. Two patients with Proteus syndrome who exhibited skeletal deformities and characteristic features such as limb length discrepancy, skin lesions, and soft tissue tumors are reported. Persistent difficulties in treating malformed spines and unequal legs, as well as unpredictable tissue reaction to trauma, are discussed.
Subject(s)
Proteus Syndrome/diagnostic imaging , Child , Child, Preschool , Female , Humans , Joint Deformities, Acquired/diagnostic imaging , Joint Deformities, Acquired/etiology , Leg Length Inequality/etiology , Male , Proteus Syndrome/complications , Radiography , Spine/abnormalities , Spine/diagnostic imagingABSTRACT
The transmural potential difference (tpd) of the gastric mucosa was investigated in relation to age and sex of the patients. The administration of acetylsalicylic acid in healthy children causes no significant decrease in gastric potential difference. In children with acute of chronic inflammatory diseases (elevated blood sedimentation velocity) the tpd was found to be increased compared with normal controls. After local ASA application a temporary, significant decrease of the tpd to normal values could be observed.
Subject(s)
Aspirin/adverse effects , Gastric Mucosa/drug effects , Inflammation/drug therapy , Acute Disease , Aspirin/therapeutic use , Blood Sedimentation , Child , Child, Preschool , Female , Gastric Juice/drug effects , Humans , Male , Membrane Potentials/drug effects , Risk Factors , Water-Electrolyte Balance/drug effectsABSTRACT
The transepithelial potential difference of the gastrointestinal mucosa as a diagnostic parameter obtains increasing importance in clinical medicine. Therefore it is necessary to consider methodical aspects of the tPD-measurement under in-vivo conditions. The current paper presents methodical considerations for instance electrode arrangement, positions, composition of the electrolyte electrodes, diffusion potentials, rate of perfusion and unstirred water layer and their influence on the tPD-measurement.
Subject(s)
Gastric Mucosa/physiology , Intestinal Mucosa/physiology , Ion Channels/physiology , Epithelium/physiology , Humans , Membrane PotentialsABSTRACT
The gastric transepithelial potential difference seems to be a sensitive parameter of the integrity of gastric mucosa. The administration of acetylsalicylic acid in adults causes a rapid and significant decrease in gastric potential difference, whereas in children this characteristic reaction fails to occur.
Subject(s)
Aspirin/pharmacology , Gastric Mucosa/drug effects , Adolescent , Adult , Age Factors , Child , Child, Preschool , Electrolytes/metabolism , Epithelium/physiology , Female , Gastric Juice/metabolism , Gastric Mucosa/physiology , Humans , Hydrogen-Ion Concentration , Male , Membrane Potentials/drug effectsABSTRACT
The transmural electric potential difference (PD) of the gastric mucosa was investigated in children, teen-agers, and adults. Acetylsalicylic acid, a well known barrier breaker, causes in adults a characteristic decrease of the gastric PD. This effect in teen-agers is considerably weaker than in adults, while in children there is no significant decrease of the potential difference after local acetylsalicylic acid application.
