Atypical intranasal foreign body.

This report records the findings of a long-standing intransasal foreign body in a six-year-old boy from a remote, semidesert region of Kenya. He had nasal obstruction for 20 months and as a result had developed chronic otitis media and severe malnutrition. Removal of the mass was accomplished piecemeal by aspiration, revealing that the entire septum and both lateral nasal walls had been destroyed by the process, thought to be due to a vegetal foreign body. Following removal of the foreign body, his health improved, the otitis media cleared up and he gained weight.

Intestinal-type adenocarcinoma of the sinonasal tract: a clinicopathologic study of 18 cases.

BACKGROUND: Intestinal-type adenocarcinoma (ITAC) of the nose and paranasal sinuses is a relatively rare tumor. It commonly affects subjects exposed to wood or leather dust. METHODS: The authors present the clinicopathologic findings of 18 cases of sinonasal ITACs and review the proposed histologic classifications. RESULTS: All patients, except one, were males; mean age was 60 years (range, 41-79); in 9 cases an occupational exposure to wood or leather dust was found. Common presenting symptoms were epistaxis, nasal obstruction and rhinorrhea. Histologically, tumors were divided into four groups: well-differentiated (G1) ITACs = 3 cases; moderately differentiated (G2) ITACs = 8 cases; poorly differentiated (G3) ITACs = 2 cases; mucinous (M) ITACs = 5 cases. Immunocytochemically, 16/17 cases were positive for carcinoembryonal antigen, 1/17 for somatostatin, and 0/16 cases for gastrin. CONCLUSIONS: Sinonasal ITACs are aggressive tumors, often diagnosed in a relatively advanced stage. Owing the close similarity of the microscopic aspects, a histologic classification of ITACs analogous to that of colonic adenocarcinomas is proposed.

[Histopathological parameters and lymphatic metastasis in supraglottic laryngeal carcinoma]. / Parametri istopatologici e metastatizzazione linfonodale nel carcinoma laringeo sopraglottico.

Histopathologic parameters in predicting lymph node metastasis of supraglottic laryngeal carcinoma. A systematic clinical-pathological study was performed on fifty-three resected cases of supraglottic laryngeal squamous cell carcinoma, followed up for at least 5 years. The aim of the research was to evaluate histopathologic parameters in predicting lymph node metastasis (N+) as expression of biological malignancy of the neoplasm. The following neoplastic microscopical features were studied: histopathologic and cytologic grading, pattern of growth, peritumoral inflammatory infiltrate, stromal reaction, tumoral necrosis. The results are as follows: stromal reaction and cytologic grading are not useful to identify N+ and N- cases. Cases with high and low degree of differentiation (Broder's grading) are significantly correlated respectively to low (14.3%) and high (70%) incidence of lymph node metastasis (p less than 0.03). A clear correlation is present between the pattern of growth "pushing" and lacking of node metastasis (84.6%). A favorable prognosis significance seems to be linked with the presence of peritumoral lymphoplasmocytic infiltrate, which results to be a marker of cases in which lymph node metastasis incidence is very low (5.5%; p less than 0.001). On the contrary lymph node metastasis incidence increase when tumoral necrosis is present (76.5%; p less than 0.001).

[Tumors of the lateral parapharyngeal space. Our case series]. / I tumori dello spazio parafaringeo laterale. Nostra casistica.

After a review of the literature, the authors present 20 cases of parapharyngeal tumors which were operated on over the past 13 years at the ENT Clinic of the University of Florence. Although diagnosis is generally made quite late, great improvement has been achieved with the new "imaging" techniques. New and better information has made it possible to choose the most suitable surgical approach. In such cases neoplasm is most frequently observed in young adults; they prove benign in most cases and are of varying oncotypes--most often of a salivary gland or neurogenic origin. Diagnosis is performed by a CT scanner with an intravenous contrast medium and by angiography of the carotid artery. More recently CT sialography and MRI have also been used. The surgical technique (transoral, transcervical, transparotid and transmandibular excision, alone or combined) was chosen according to localization, size and vascularity. Follow-up data show a high incidence of recovery (85%) with acceptable functional results.