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1.
Tumori ; 102(1): 96-102, 2016.
Article in English | MEDLINE | ID: mdl-26797934

ABSTRACT

PURPOSE: Patients treated for head and neck cancer present some of the most significant posttreatment morbidity of any group of patients with cancer. Our aim is to describe quality of life and psychological distress after different treatments among head and neck cancer patients during the first year after treatment. METHODS: A total of 86 patients treated for head and neck cancer were evaluated within 1 year of the end of treatment by means of the Distress Thermometer (DT) and EORTC C30 and H&N35 questionnaires. Type of treatment was classified into 3 groups: surgery, chemo-/radiotherapy, and combined treatment. RESULTS: Forty-one percent of patients showed a high level of distress (DT >5). Distress was higher in patients with a tracheotomy or with previous cancer in another district. Quality of life was homogeneous across treatment types after adjustment for stage and time since end of treatment, except for higher levels of suffering related to sensory problems, social eating, and dry mouth among patients treated with combined therapy. CONCLUSIONS: The DT and EORTC questionnaires proved to be effective and easy tools to monitor distress and quality of life in patients with head and neck cancer. Monitoring the quality of life perceived by each patient during his/her course of treatment could be useful in planning the rehabilitation process while performing follow-up visits.


Subject(s)
Head and Neck Neoplasms/psychology , Head and Neck Neoplasms/therapy , Quality of Life , Stress, Psychological/etiology , Adult , Aged , Appetite/drug effects , Appetite/radiation effects , Combined Modality Therapy , Constipation/etiology , Deglutition Disorders/etiology , Diarrhea/etiology , Dyspnea/etiology , Eating , Fatigue/etiology , Female , Head and Neck Neoplasms/complications , Head and Neck Neoplasms/physiopathology , Health Status , Humans , Male , Middle Aged , Nausea/etiology , Pain/etiology , Self Report , Sexual Behavior/drug effects , Sexual Behavior/radiation effects , Sleep Initiation and Maintenance Disorders/etiology , Speech Disorders/etiology
2.
Head Neck ; 30(8): 1064-71, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18528900

ABSTRACT

BACKGROUND: The main concern in the treatment of laryngeal carcinomas is tumor control with preservation of laryngeal functions. We believe that salvage supracricoid partial laryngectomy (SPL) should be carefully considered in selected cases of radiotherapy failure, because it can offer the possibility of achieving adequate tumor control with preservation of laryngeal functions. METHODS: A series of 31 patients who underwent an SPL as salvage procedure after radiotherapy failure was reviewed. RESULTS: Locoregional control rate was 75%, with 60% 5-year overall survival; no patients were lost to follow-up, and a death-from-disease rate of 19.35% was recorded. Restoration of laryngeal functions was achieved in 89.29% of the patients. No statistically significant differences were found in locoregional control regarding anterior commissure involvement, elective neck dissection versus wait-and-see policy, pathologic positive neck disease, and restage I-II versus restage III-IV. CONCLUSION: The oncologic and functional results indicate the consistency of salvage SPL, proposing this type of operation as a serious alternative to total laryngectomy in carefully selected cases.


Subject(s)
Carcinoma, Squamous Cell/surgery , Laryngeal Neoplasms/surgery , Laryngectomy/methods , Neoplasm Recurrence, Local/surgery , Salvage Therapy , Adult , Aged , Carcinoma, Squamous Cell/mortality , Carcinoma, Squamous Cell/radiotherapy , Cricoid Cartilage/surgery , Female , Humans , Laryngeal Neoplasms/mortality , Laryngeal Neoplasms/radiotherapy , Male , Middle Aged , Neck Dissection , Neoplasm Recurrence, Local/pathology , Retrospective Studies , Treatment Failure
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