1.
J Surg Oncol
; 52(2): 115-8, 1993 Feb.
Article
in English
| MEDLINE
| ID: mdl-8468974
ABSTRACT
The thymidylate synthase (TS) inhibition rate was measured after tegafur (FT) administration (1.5 g/day, at least 10 days) in 7 sigmoid colon cancer patients. The TS inhibition rate decreased as the interval between the time of the last administration and the time of the tumor resection increased longer. This study provides basic data for considering methods of drug administration and assessment of modification, for example, by leucovorin.