1.
J Asian Nat Prod Res
; 7(2): 121-6, 2005 Apr.
Article
in English
| MEDLINE
| ID: mdl-15621613
ABSTRACT
A convenient method for the stereoselective syntheses of beta-amino acids with alpha-substitutions has been developed. This synthetic route involves the preparation of isoxazolidinones through hydroxylamine addition to unsaturated esters and subsequent hydrogenation. This procedure is also useful for the stereoselective syntheses of alpha-deuterated beta-amino acids.